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Western Blot (WB) (Western blot analysis of TWIK2 expression in HT29 (A), K562 (B), mouse heart (C) whole cell lysates.)

Rabbit TWIK2 Polyclonal Antibody | anti-TWIK2 antibody

Anti-TWIK2 Antibody

Gene Names
KCNK6; TOSS; KCNK8; TWIK2; K2p6.1; TWIK-2
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
TWIK2; Polyclonal Antibody; Anti-TWIK2 Antibody; TOSS; Potassium channel subfamily K member 6; Inward rectifying potassium channel protein TWIK-2; TWIK-originated similarity sequence; anti-TWIK2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of TWIK2 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-TWIK2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human TWIK2. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of TWIK2 expression in HT29 (A), K562 (B), mouse heart (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of TWIK2 expression in HT29 (A), K562 (B), mouse heart (C) whole cell lysates.)
Related Product Information for anti-TWIK2 antibody
Rabbit polyclonal antibody to TWIK2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,747 Da
NCBI Official Full Name
potassium channel subfamily K member 6
NCBI Official Synonym Full Names
potassium channel, subfamily K, member 6
NCBI Official Symbol
KCNK6
NCBI Official Synonym Symbols
TOSS; KCNK8; TWIK2; K2p6.1; TWIK-2
NCBI Protein Information
potassium channel subfamily K member 6; K2P6.1 potassium channel; TWIK-originated similarity sequence; TWIK-originated sodium similarity sequence; inward rectifying potassium channel protein TWIK-2
UniProt Protein Name
Potassium channel subfamily K member 6
UniProt Gene Name
KCNK6
UniProt Synonym Gene Names
TOSS; TWIK2
UniProt Entry Name
KCNK6_HUMAN

NCBI Description

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This channel protein, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNK6: Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: voltage-gated potassium channel complex; plasma membrane

Molecular Function: inward rectifier potassium channel activity

Biological Process: synaptic transmission; negative regulation of systemic arterial blood pressure; regulation of resting membrane potential; potassium ion transport

Research Articles on TWIK2

Similar Products

Product Notes

The TWIK2 kcnk6 (Catalog #AAA8307047) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TWIK2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TWIK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TWIK2 kcnk6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TWIK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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