Immunohistochemistry (IHC)
(Anti-TUBGCP4 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Rabbit anti-Mouse, Human TUBGCP4 Polyclonal Antibody | anti-TUBGCP4 antibody
Anti-TUBGCP4 Antibody (aa191-240) IHC-plus
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunohistochemistry (IHC)
(Anti-TUBGCP4 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC)
(Anti-TUBGCP4 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Western Blot (WB)
(Western blot of extracts from COLO/HT-29 cells, using TUBGCP4 Antibody. The lane on the right is treated with the synthesized peptide.)
Western Blot (WB)
(Western blot of extracts from COLO/HT-29 cells, using TUBGCP4 Antibody. The lane on the right is treated with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Uniprot Description
TUBGCP4: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q15
Cellular Component: centrosome; cytosol; gamma-tubulin complex; gamma-tubulin ring complex; membrane; microtubule; microtubule cytoskeleton; recycling endosome; spindle pole body
Molecular Function: gamma-tubulin binding; microtubule minus-end binding; protein binding; structural constituent of cytoskeleton
Biological Process: centrosome duplication; cytoplasmic microtubule organization and biogenesis; G2/M transition of mitotic cell cycle; interphase microtubule nucleation by interphase microtubule organizing center; meiosis; microtubule nucleation; mitotic cell cycle; protein complex assembly
Disease: Microcephaly And Chorioretinopathy, Autosomal Recessive, 3
Research Articles on TUBGCP4
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Product Notes
The TUBGCP4 tubgcp4 (Catalog #AAA2400363) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TUBGCP4 Antibody (aa191-240) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's TUBGCP4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:10000) IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the TUBGCP4 tubgcp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TUBGCP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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