Human Protein max ELISA Kit | MAX elisa kit

Human Protein max ELISA Kit

Cat. Num. AAA2885874

• Gene Names: MAX; bHLHd4
• Reactivity: Human
• Synonyms: Protein max; Human Protein max ELISA Kit; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X; MAX; BHLHD4; MAX elisa kit

• Reactivity: Human
• Sequence Length: 87

• Assay Type: Sandwich
• Detection Range: 0.156-10 ng/mL
• Sensitivity: 0.067ng/mL
• Intra-Assay CV: <=5.1%
• Inter-Assay CV: <=8.3%
• Recovery: 99%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 402794193
• NCBI GeneID: 4149
• NCBI Accession #: NP_001257997.1
• NCBI GenBank Nucleotide #: NM_001271068.1
• UniProt Accession #: P61244; P25912; P52163; Q14803; Q96CY8; A6NH73; A8K265; A8K4G4; A8K824
• Molecular Weight: 9,599 Da
• NCBI Official Full Name: protein max isoform g
• NCBI Official Synonym Full Names: MYC associated factor X
• NCBI Official Symbol: MAX
• NCBI Official Synonym Symbols: bHLHd4
• NCBI Protein Information: protein max
• UniProt Protein Name: Protein max
• Protein Family: Protein max
• UniProt Gene Name: MAX
• UniProt Synonym Gene Names: BHLHD4; bHLHd4
• UniProt Entry Name: MAX_HUMAN

NCBI Description

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Description

Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.