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Western Blot (WB) (Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 μg/mL.)

Rabbit anti-Human TTYH1 Polyclonal Antibody | anti-TTYH1 antibody

TTYH1 Antibody

Reactivity
Human
Applications
ELISA, Western Blot, Immunocytochemistry
Purity
TTYH1 Antibody is affinity chromatography purified via peptide column.
Synonyms
TTYH1; Polyclonal Antibody; TTYH1 Antibody; Protein tweety homolog 1; hTTY1; tweety homolog 1 (Drosophila); anti-TTYH1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
TTYH1 antibody is human specific. Multiple isoforms of TTYH1 are known to exist.
Purity/Purification
TTYH1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
460
Applicable Applications for anti-TTYH1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
TTYH1 antibody can be used for detection of TTYH1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL.
Conjugate
Unconjugated
Immunogen
TTYH1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TTYH1.
Buffer
TTYH1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TTYH1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 μg/mL.)

Western Blot (WB) (Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 μg/mL.)

Immunocytochemistry (IHC)

(Immunocytochemistry of TTYH1 in Raji cells with TTYH1 antibody at 5 μg/mL.)

Immunocytochemistry (IHC) (Immunocytochemistry of TTYH1 in Raji cells with TTYH1 antibody at 5 μg/mL.)
Related Product Information for anti-TTYH1 antibody
TTYH1 Antibody: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,119 Da
NCBI Official Full Name
protein tweety homolog 1 isoform 2
NCBI Official Synonym Full Names
tweety family member 1
NCBI Official Symbol
TTYH1
NCBI Protein Information
protein tweety homolog 1; hTTY1
UniProt Protein Name
Protein tweety homolog 1
Protein Family
UniProt Gene Name
TTYH1
UniProt Synonym Gene Names
hTTY1
UniProt Entry Name
TTYH1_HUMAN

NCBI Description

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011]

Uniprot Description

TTYH1: Probable chloride channel. May be involved in cell adhesion. Belongs to the tweety family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, integral; Transporter, ion channel; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: filopodium tip; filopodium membrane; integral to membrane; plasma membrane; smooth endoplasmic reticulum membrane

Molecular Function: iron ion transmembrane transporter activity; calcium ion binding

Biological Process: mitosis; cell-cell adhesion; filopodium formation; chloride transport; iron ion transport; transmembrane transport; cell-substrate adhesion

Research Articles on TTYH1

Similar Products

Product Notes

The TTYH1 ttyh1 (Catalog #AAA150115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TTYH1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TTYH1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC). TTYH1 antibody can be used for detection of TTYH1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the TTYH1 ttyh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTYH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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