Western Blot (WB)
(Western blot analysis of TTBK1 Antibody (N-term) in mouse testis tissue lysates (35ug/lane). TTBK1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse TTBK1 Polyclonal Antibody | anti-TTBK1 antibody
TTBK1 Antibody (N-term)
Gene Names
TTBK1; BDTK
Reactivity
Human, mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TTBK1; Polyclonal Antibody; TTBK1 Antibody (N-term); Tau-tubulin kinase 1; Brain-derived tau kinase; BDTK; KIAA1855; anti-TTBK1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TTBK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-258 amino acids from the N-terminal region of human TTBK1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.47 (varies by lot)
Sequence Positions
230-258
Sequence Length
1321
Applicable Applications for anti-TTBK1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of TTBK1 Antibody (N-term) in mouse testis tissue lysates (35ug/lane). TTBK1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of TTBK1 Antibody (N-term) in mouse testis tissue lysates (35ug/lane). TTBK1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(TTBK1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TTBK1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-TTBK1 antibody
TTBK1 is Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.
Product Categories/Family for anti-TTBK1 antibody
References
Sato, S., et al. J. Neurosci. 28(53):14511-14521(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Mungall, A.J., et al. Nature 425(6960):805-811(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
142737
NCBI Official Full Name
tau-tubulin kinase 1
NCBI Official Synonym Full Names
tau tubulin kinase 1
NCBI Official Symbol
TTBK1
NCBI Official Synonym Symbols
BDTK
NCBI Protein Information
tau-tubulin kinase 1
UniProt Protein Name
Tau-tubulin kinase 1
Protein Family
UniProt Gene Name
TTBK1
UniProt Synonym Gene Names
BDTK; KIAA1855
UniProt Entry Name
TTBK1_HUMAN
Uniprot Description
TTBK1: Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CK1; Kinase, protein; EC 2.7.11.1; CK1 group; TTBK family
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; ATP binding
Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; substantia nigra development
Research Articles on TTBK1
Similar Products
Product Notes
The TTBK1 ttbk1 (Catalog #AAA9206620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 230-258. The TTBK1 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TTBK1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TTBK1 ttbk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTBK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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