Western Blot (WB)
(Western blot analysis of TSYL2 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse TSYL2 Polyclonal Antibody | anti-TSYL2 antibody
TSYL2 Antibody
Gene Names
TSPYL2; CDA1; CTCL; NP79; TSPX; CINAP; DENTT; SE204; HRIHFB2216
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
TSYL2; Polyclonal Antibody; TSYL2 Antibody; CASK interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; CINAP; CTCL; CTCL tumor antigen se20 4; CTCL-associated antigen se20-4; Cutaneous T cell lymphoma associated antigen se20 4; Cutaneous T cell lymphoma associated tumor antigen se20 4; Cutaneous T-cell lymphoma-associated antigen se20-4; Differentially Expressed Nucleolar TGF beta1 Target; Differentially Expressed Nucleolar TGF beta1 Target protein; Differentially-expressed nucleolar TGF-beta1 target protein; HRIHFB2216; NP79; Nuclear protein of 79 kDa; RP1 290F12.2; SE20 4; SE204; Testis specific protein Y encoded like 2; testis-specific protein Y encoded-like 2; Testis-specific Y-encoded-like protein 2; TSPX; TSPY like 2; TSPY like protein 2; TSPY-like protein 2; TSPYL2; TSYL2_HUMAN; anti-TSYL2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
TSYL2 antibody detects endogenous levels of total TSYL2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
693
Applicable Applications for anti-TSYL2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.
Tissue Specificity
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of TSYL2 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of TSYL2 expression in HEK293 cells, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-TSYL2 antibody
Function: Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Subunit Structure: Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TBR1 and TSPYL2 (By similarity).
Post-translational Modifications: Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
Similarity: Belongs to the nucleosome assembly protein (NAP) family.
Subunit Structure: Interacts with histones. Interacts with CASK. Part of a complex containing CASK, TBR1 and TSPYL2 (By similarity).
Post-translational Modifications: Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
Similarity: Belongs to the nucleosome assembly protein (NAP) family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 80 kDa
NCBI Official Full Name
testis-specific Y-encoded-like protein 2
NCBI Official Synonym Full Names
TSPY like 2
NCBI Official Symbol
TSPYL2
NCBI Official Synonym Symbols
CDA1; CTCL; NP79; TSPX; CINAP; DENTT; SE204; HRIHFB2216
NCBI Protein Information
testis-specific Y-encoded-like protein 2
UniProt Protein Name
Testis-specific Y-encoded-like protein 2
UniProt Gene Name
TSPYL2
UniProt Synonym Gene Names
CDA1; DENTT; TSPX; TSPY-like protein 2; CTCL-associated antigen se20-4; NP79
NCBI Description
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth. [provided by RefSeq, Sep 2009]
Uniprot Description
Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Research Articles on TSYL2
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Product Notes
The TSYL2 tspyl2 (Catalog #AAA9603980) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSYL2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSYL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TSYL2 tspyl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSYL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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