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Western Blot (WB) (TSPYL5 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TSPYL5 antibody detected the TSPYL5 protein (arrow).)

Rabbit anti-Mouse TSPYL5 Polyclonal Antibody | anti-TSPYL5 antibody

TSPYL5 Antibody (C-term)

Reactivity
Mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TSPYL5; Polyclonal Antibody; TSPYL5 Antibody (C-term); Testis-specific Y-encoded-like protein 5; TSPY-like protein 5; KIAA1750; anti-TSPYL5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TSPYL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-372 amino acids from the C-terminal region of human TSPYL5.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.34 (varies by lot)
Sequence Positions
344-372
Sequence Length
417
Applicable Applications for anti-TSPYL5 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(TSPYL5 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TSPYL5 antibody detected the TSPYL5 protein (arrow).)

Western Blot (WB) (TSPYL5 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TSPYL5 antibody detected the TSPYL5 protein (arrow).)

Immunohistochemistry (IHC)

(TSPYL5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TSPYL5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (TSPYL5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TSPYL5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-TSPYL5 antibody
The function of this protein remains unknown.
Product Categories/Family for anti-TSPYL5 antibody
References
Kim, E.J., et al. Biochem. Biophys. Res. Commun. 392(3):448-453(2010)
Jung, Y., et al. Lab. Invest. 88(2):153-160(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45143
NCBI Official Full Name
testis-specific Y-encoded-like protein 5
NCBI Official Synonym Full Names
TSPY-like 5
NCBI Official Symbol
TSPYL5
NCBI Protein Information
testis-specific Y-encoded-like protein 5
UniProt Protein Name
Testis-specific Y-encoded-like protein 5
UniProt Gene Name
TSPYL5
UniProt Synonym Gene Names
KIAA1750; TSPY-like protein 5
UniProt Entry Name
TSYL5_HUMAN

Uniprot Description

TSPYL5: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7. Belongs to the nucleosome assembly protein (NAP) family.

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: nucleosome assembly; positive regulation of protein kinase B signaling cascade; positive regulation of protein ubiquitination; regulation of growth; positive regulation of cell proliferation

Research Articles on TSPYL5

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Product Notes

The TSPYL5 tspyl5 (Catalog #AAA9208697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 344-372. The TSPYL5 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSPYL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the TSPYL5 tspyl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSPYL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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