Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse brain tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes)
Rabbit anti-Human, Mouse TSPYL1 Polyclonal Antibody | anti-TSPYL1 antibody
TSPYL1 Antibody
Immunohistochemistry: 1:25-1:100
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse brain tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes)
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Mouse brain tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes)
NCBI and Uniprot Product Information
Uniprot Description
TSPYL1: Defects in TSPYL1 are the cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). SIDDT is an autosomal recessive disorder. Affected infants appear normal at birth, develop signs of visceroautonomic dysfunction early in life, and die before 12 months of age of abrupt cardiorespiratory arrest. Features included bradycardia, hypothermia, severe gastroesophageal reflux, laryngospasm, bronchospasm, and abnormal cardiorespiratory patterns during sleep. Genotypic males with SIDDT had fetal testicular dysgenesis and ambiguous genitalia, with findings such as intraabdominal testes, dysplastic testes, deficient fetal testosterone production, fusion and rugation of the gonadal sac, and partial development of the penile shaft. Female sexual development was normal. Affected infants had an unusual staccato cry, similar to the cry of a goat. Belongs to the nucleosome assembly protein (NAP) family.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 6q22.1
Cellular Component: nucleolus; nucleus
Molecular Function: enzyme binding
Disease: Sudden Infant Death With Dysgenesis Of The Testes Syndrome
Similar Products
Product Notes
The TSPYL1 tspyl1 (Catalog #AAA9415435) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSPYL1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TSPYL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the TSPYL1 tspyl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSPYL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
