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Western Blot (WB) (TSH-alpha Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TSH-alpha antibody detected the TSH-alpha protein (arrow).)

Rabbit anti-Human TSH-alpha Polyclonal Antibody | anti-CGA antibody

TSH-alpha Antibody (C-term)

Gene Names
CGA; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TSH-alpha; Polyclonal Antibody; TSH-alpha Antibody (C-term); Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; Thyrotropin alpha chain; CGA; anti-CGA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TSH-alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human TSH-alpha.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.37 (varies by lot)
Sequence Positions
74-103
Sequence Length
116
Applicable Applications for anti-CGA antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(TSH-alpha Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TSH-alpha antibody detected the TSH-alpha protein (arrow).)

Western Blot (WB) (TSH-alpha Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TSH-alpha antibody detected the TSH-alpha protein (arrow).)
Related Product Information for anti-CGA antibody
The four human glycoprotein hormones chorionic
gonadotropin (CG), luteinizing hormone (LH), follicle stimulating
hormone (FSH), and thyroid stimulating hormone (TSH) are dimers
consisting of alpha and beta subunits that are associated
noncovalently. The alpha subunits of these hormones are identical,
however, their beta chains are unique and confer biological
specificity. The protein encoded by this gene is the alpha subunit
and belongs to the glycoprotein hormones alpha chain family.
Product Categories/Family for anti-CGA antibody
References
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Panicker, V., et al. Am. J. Hum. Genet. 87(3):430-435(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Robinson, N., et al. Clin. Lab. 56 (5-6), 197-206 (2010) :
Bjerner, J., et al. Scand. J. Clin. Lab. Invest. 69(8):873-879(2009)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13075
NCBI Official Full Name
glycoprotein hormones alpha chain isoform 2
NCBI Official Synonym Full Names
glycoprotein hormones, alpha polypeptide
NCBI Official Symbol
CGA
NCBI Official Synonym Symbols
HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA
NCBI Protein Information
glycoprotein hormones alpha chain
UniProt Protein Name
Glycoprotein hormones alpha chain
Protein Family
UniProt Gene Name
CGA
UniProt Synonym Gene Names
CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
UniProt Entry Name
GLHA_HUMAN

NCBI Description

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6q12-q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; positive regulation of cell proliferation; peptide hormone processing; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration

Research Articles on CGA

Similar Products

Product Notes

The CGA cga (Catalog #AAA9211571) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 74-103. The TSH-alpha Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TSH-alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CGA cga for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSH-alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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