Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissue using Tsc2 antibody (Ser939))
Rabbit Tsc2 Polyclonal Antibody | anti-TSC2 antibody
TSC2 Antibody (Ser939)
Gene Names
Tsc2; Rc
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Tsc2; Polyclonal Antibody; TSC2 Antibody (Ser939); Rabbit Polyclonal TSC2 Antibody (Ser939); Polyclonal TSC2 antibody; Anti-TSC2 antibody; tuberous sclerosis 2 antibody; Tuberous sclerosis 2 protein antibody; FLJ43106 antibody; LAM antibody; TSC-2 antibody; TSC4 antibody; Tuberin antibody; anti-TSC2 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
Tsc2 antibody (Ser939) detects endogenous levels of Tsc2 only when phosphorylated at serine 939
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
1
Applicable Applications for anti-TSC2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:100
ELISA: 1:4000
IHC: 1:50-1:100
ELISA: 1:4000
Immunogen
Tsc2 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human Tsc2 around the phosphorylation site of serine 939 (S-T-SP-L-N) as the immunogen.
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissue using Tsc2 antibody (Ser939))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissue using Tsc2 antibody (Ser939))
Related Product Information for anti-TSC2 antibody
Tsc2, in complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1.
Product Categories/Family for anti-TSC2 antibody
NCBI and Uniprot Product Information
NCBI Description
acts as a tumor suppressor; may play a role in cell cycle regulation; acute phase response, and negative regulation of cell proliferation [RGD, Feb 2006]
Research Articles on TSC2
Similar Products
Product Notes
The TSC2 (Catalog #AAA5313765) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Tsc2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:1000 IHC: 1:50-1:100 ELISA: 1:4000. Researchers should empirically determine the suitability of the TSC2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tsc2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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