Western Blot (WB)
(Western blot analysis of anti-CHAK1 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CHAK1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human TRPM7 Polyclonal Antibody | anti-TRPM7 antibody
TRPM7, CT (Transient Receptor Potential Cation Channel Subfamily M Member 7, Long Transient Receptor Potential Channel 7, LTrpC-7, Channel-kinase 1, CHAK1, LTRPC7) (APC)
Gene Names
TRPM7; CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein G Affinity Chromatography.
Synonyms
TRPM7; Polyclonal Antibody; CT (Transient Receptor Potential Cation Channel Subfamily M Member 7; Long Transient Receptor Potential Channel 7; LTrpC-7; Channel-kinase 1; CHAK1; LTRPC7) (APC); anti-TRPM7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human TRPM7.
Purity/Purification
Purified by Protein G Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Sequence Length
1865
Applicable Applications for anti-TRPM7 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-1:100
FLISA: 1:1,000
WB: 1:50-1:200
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:50-1:200
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human TRPM7 (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis of anti-CHAK1 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CHAK1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CHAK1 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CHAK1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Western Blot (WB)
(CHAK1 Antibody (F1835) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CHAK1 antibody detected the CHAK1 protein (arrow).)
Western Blot (WB)
(CHAK1 Antibody (F1835) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CHAK1 antibody detected the CHAK1 protein (arrow).)
Product Categories/Family for anti-TRPM7 antibody
References
1. Blume-Jensen P, et al. Nature 2001. 411: 355. 2. Cantrell D, J. Cell Sci. 2001. 114: 1439. 3. Jhiang S Oncogene 2000. 19: 5590. 4. Manning G, et al. Science 2002. 298: 1912. 5. Moller, D, et al. Am. J. Physiol. 1994. 266: C351-C359. 6.Robertson, S. et al. Trends Genet. 2000. 16: 368. 7.Robinson D, et al. Oncogene 2000. 19: 5548. 8.Van der Ven, P, et al. Hum. Molec. Genet. 1993. 2: 1889. 9.Vanhaesebroeck, B, et al. Biochem. J. 2000. 346: 561. 10.Van Weering D, et al. Recent Results Cancer Res. 1998. 154: 271.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
212.609
NCBI Official Full Name
Transient receptor potential cation channel subfamily M member 7
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily M member 7
NCBI Official Symbol
TRPM7
NCBI Official Synonym Symbols
CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK
NCBI Protein Information
transient receptor potential cation channel subfamily M member 7
Protein Family
NCBI Description
This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]
Research Articles on TRPM7
Similar Products
Product Notes
The TRPM7 (Catalog #AAA6503825) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRPM7, CT (Transient Receptor Potential Cation Channel Subfamily M Member 7, Long Transient Receptor Potential Channel 7, LTrpC-7, Channel-kinase 1, CHAK1, LTRPC7) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPM7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-1:100 FLISA: 1:1,000 WB: 1:50-1:200 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TRPM7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPM7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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