IHC (Immunohistchemistry)

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IHC (Immunohistchemistry) (Immunohistochemistry of paraffin-embedded human breast cancer using TGFB1 Rabbit pAb.)

Rabbit TGFB1 Polyclonal Antibody | anti-TGFB1 antibody

TGFB1 Rabbit Polyclonal Antibody

Gene Names

TGFB1; CED; LAP; DPD1; TGFB; TGFbeta

Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunohistochemistry, Immunofluorescence

Purity

Affinity purification

Synonyms

TGFB1; Polyclonal Antibody; TGFB1 Rabbit Polyclonal Antibody; CED; DPD1; LAP; TGFB; TGFbeta; TGF-??; anti-TGFB1 antibody

Ordering

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Isotype

IgG

Purity/Purification

Affinity purification

Form/Format

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applicable Applications for anti-TGFB1 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes

WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Immunogen

Recombinant fusion protein of human TGFB1 (NP_000651.3).

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

IHC (Immunohistchemistry)

(Immunohistochemistry of paraffin-embedded human breast cancer using TGFB1 Rabbit pAb.)

IF (Immunofluorescence)

(Immunofluorescence analysis of PC-12 cells using TGFB1 antibody.)

IF (Immunofluorescence)

(Immunofluorescence analysis of NIH/3T3 cells using TGFB1 antibody.)

IF (Immunofluorescence)

(Immunofluorescence analysis of U2OS cells using TGFB1 antibody.)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human brain using TGFB1 Rabbit pAb.)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using TGFB1 antibody.)

Related Product Information for anti-TGFB1 antibody

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Product Categories/Family for anti-TGFB1 antibody

Primary Antibody

NCBI and Uniprot Product Information

NCBI GI #

63025222

NCBI GeneID

7040

NCBI Accession #

NP_000651.3

NCBI GenBank Nucleotide #

NM_000660.4

UniProt Accession #

P01137; Q9UCG4; A8K792

Molecular Weight

44,341 Da

NCBI Official Full Name

transforming growth factor beta-1

NCBI Official Synonym Full Names

transforming growth factor, beta 1

NCBI Official Symbol

TGFB1

NCBI Official Synonym Symbols

CED; LAP; DPD1; TGFB; TGFbeta

NCBI Protein Information

transforming growth factor beta-1; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide

UniProt Protein Name

Transforming growth factor beta-1

UniProt Gene Name

TGFB1

UniProt Synonym Gene Names

TGFB; TGF-beta-1; LAP

UniProt Entry Name

TGFB1_HUMAN

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Product Notes

The TGFB1 tgfb1 (Catalog #AAA30644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TGFB1 Rabbit Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TGFB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the TGFB1 tgfb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGFB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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