Rabbit anti-Human TRMT61B Polyclonal Antibody | anti-TRMT61B antibody
TRMT61B Antibody
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TRMT61B; Polyclonal Antibody; TRMT61B Antibody; DKFZp564I2178; FLJ20628; tRNA methyltransferase 61 homolog B (S. cerevisiae); tRNA methyltransferase 61 homolog B; anti-TRMT61B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TRMT61B Antibody detects endogenous levels of TRMT61B.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TRMT61B antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human TRMT61B.
Conjugation
Unconjugated
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
Subunit Structure
Homooligomer; in contrast to TRMT61A, does not form a heterotetramer.
Function
Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (deciphering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (deciphering codons UCA, UCU, UCG or UCC). Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function. In addition to tRNA N(1)-methyltransferase activity, also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA, leading to interfere with mitochondrial translation.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TRMT61B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,965 Da
NCBI Official Full Name
tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial
NCBI Official Synonym Full Names
tRNA methyltransferase 61 homolog B (S. cerevisiae)
NCBI Official Symbol
TRMT61B
NCBI Protein Information
tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial; tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial; potential tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B; potential tRNA (adenine(58)-N(1))-methyltransferase catalytic s
UniProt Protein Name
tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial
Protein Family
UniProt Gene Name
TRMT61B
UniProt Entry Name
TR61B_HUMAN
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Product Notes
The TRMT61B trmt61b (Catalog #AAA9631273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRMT61B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRMT61B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TRMT61B trmt61b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRMT61B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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