Rabbit anti-Human TRMT1 Polyclonal Antibody | anti-TRMT1 antibody

TRMT1, NT (TRMT1, tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase)

Cat. Num. AAA649794

• Gene Names: TRMT1; TRM1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: TRMT1; Polyclonal Antibody; NT (TRMT1; tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA 2; 2-dimethylguanosine-26 methyltransferase; tRNA(guanine-26; N(2)-N(2)) methyltransferase; tRNA(m(2; 2)G26)dimethyltransferase); Anti -TRMT1; anti-TRMT1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-TRMT1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: TRMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-114 amino acids from the N-terminal region of human TRMT1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TRMT1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the TRMT1 antibody detected the TRMT1 protein (arrow).)

Related Product Information for anti-TRMT1 antibody

Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

Product Categories/Family for anti-TRMT1 antibody

Antibodies; Abs to Enzymes; Methyltransferase

NCBI and Uniprot Product Information

• NCBI GI #: 17390714
• NCBI GeneID: 55621
• UniProt Accession #: Q9NXH9; O76103; Q548Y5; Q8WVA6
• Molecular Weight: 72,234 Da
• NCBI Official Full Name: TRMT1 protein
• NCBI Official Synonym Full Names: tRNA methyltransferase 1 homolog (S. cerevisiae)
• NCBI Official Symbol: TRMT1
• NCBI Official Synonym Symbols: TRM1
• NCBI Protein Information: tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA(m(2,2)G26)dimethyltransferase; TRM1 tRNA methyltransferase 1 homolog; tRNA(guanine-26,N(2)-N(2)) methyltransferase; tRNA 2,2-dimethylguanosine-26 methyltransferase; N(2),N(2)-dimethylguanosine tRNA methyltransferase
• UniProt Protein Name: tRNA (guanine(26)-N(2))-dimethyltransferase
• Protein Family: TRMT1-like protein
• UniProt Gene Name: TRMT1
• UniProt Entry Name: TRM1_HUMAN

Uniprot Description

Function: Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

Catalytic activity: 2 S-adenosyl-L-methionine + guanine26 in tRNA = 2 S-adenosyl-L-homocysteine + N(2)-dimethylguanine26 in tRNA.

Sequence similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.Contains 1 C3H1-type zinc finger.Contains 1 Trm1 methyltransferase domain.