Rabbit anti-Human TRIP11 Polyclonal Antibody | anti-TRIP11 antibody
TRIP11 Antibody
Gene Names
TRIP11; ACG1A; CEV14; TRIP-11; TRIP230; GMAP-210
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
TRIP11; Polyclonal Antibody; TRIP11 Antibody; CEV 14; CEV14; Clonal evolution related gene on chromosome 14; GMAP 210; GMAP210; Golgi associated microtubule binding protein 210; Thyroid hormone receptor interactor 11; Thyroid receptor interacting protein 11; TRIP 11; TRIP 230; anti-TRIP11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
TRIP11 Antibody detects endogenous levels of TRIP11.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TRIP11 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human TRIP11.
Conjugation
Unconjugated
Similarity
Extended rod-like protein with coiled-coil domains. The C-terminus is required for recruitment to the Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment.
Subunit Structure
Interacts with the active form of RAB2A. Interacts with IFT20. Binds RB1.
Tissue Specificity
Highly expressed in pancreas, muscle, heart, testis, peripheral blood leukocytes, and in several leukemia cell lines. Detected at intermediate levels in placenta and kidney, and at low levels in brain and lung. Isoform 1 and isoform 2 are expressed in articular chondrocytes.
Function
Is a membrane tether required for vesicle tethering to Golgi. Has an essential role in the maintenance of Golgi structure and function. It is required for efficient anterograde and retrograde trafficking in the early secretory pathway, functioning at both the ER-to-Golgi intermediate compartment (ERGIC) and Golgi complex. Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription.
Note
Associates with the ends of centrosome-nucleated microtubules.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TRIP11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
227,586 Da
NCBI Official Full Name
thyroid receptor-interacting protein 11
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 11
NCBI Official Symbol
TRIP11
NCBI Official Synonym Symbols
ACG1A; CEV14; TRIP-11; TRIP230; GMAP-210
NCBI Protein Information
thyroid receptor-interacting protein 11; Golgi-microtubule-associated protein of 210 kDa; TR-interacting protein 11; clonal evolution-related gene on chromosome 14 protein; golgi-associated microtubule-binding protein 210
UniProt Protein Name
Thyroid receptor-interacting protein 11
Protein Family
UniProt Gene Name
TRIP11
UniProt Synonym Gene Names
CEV14
UniProt Entry Name
TRIPB_HUMAN
Similar Products
Product Notes
The TRIP11 trip11 (Catalog #AAA9629941) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIP11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRIP11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TRIP11 trip11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIP11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
