Rabbit anti-Human TRIM26 Polyclonal Antibody | anti-TRIM26 antibody

TRIM26, NT (TRIM26, RNF95, ZNF173, Tripartite motif-containing protein 26, Acid finger protein, RING finger protein 95, Zinc finger protein 173) (PE)

Cat. Num. AAA6358241

• Gene Names: TRIM26; AFP; RNF95; ZNF173
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TRIM26; Polyclonal Antibody; NT (TRIM26; RNF95; ZNF173; Tripartite motif-containing protein 26; Acid finger protein; RING finger protein 95; Zinc finger protein 173) (PE); Zinc finger protein 173; anti-TRIM26 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 539

• Applicable Applications for anti-TRIM26 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TRIM26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the N-terminal region of human TRIM26.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TRIM26 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TRIM26 antibody detected the TRIM26 protein (arrow).)

Related Product Information for anti-TRIM26 antibody

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6.

Product Categories/Family for anti-TRIM26 antibody

Antibodies; Transcription Factors; TRIM (Tripartite Motif)

References

Cree, B.A., et al. PLoS ONE 5 (6), E11296 (2010): Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009): Males, S., et al. Antivir. Ther. (Lond.) 12(5):797-803(2007). Reymond, A., et al. EMBO J. 20(9):2140-2151(2001). Rahman, A., et al. J. Biol. Chem. 273(25):15395-15403(1998).

NCBI and Uniprot Product Information

• NCBI GI #: 4508005
• NCBI GeneID: 7726
• NCBI Accession #: NP_003440.1
• NCBI GenBank Nucleotide #: NP_003440.1
• UniProt Accession #: Q12899
• NCBI Official Full Name: tripartite motif-containing protein 26
• NCBI Official Synonym Full Names: tripartite motif containing 26
• NCBI Official Symbol: TRIM26
• NCBI Official Synonym Symbols: AFP; RNF95; ZNF173
• NCBI Protein Information: tripartite motif-containing protein 26
• UniProt Protein Name: Tripartite motif-containing protein 26
• Protein Family: Tripartite motif-containing protein
• UniProt Gene Name: TRIM26
• UniProt Synonym Gene Names: RNF95; ZNF173; AFP
• UniProt Entry Name: TRI26_HUMAN

NCBI Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

TRIM26: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]

Protein type: DNA-binding; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: cytosol

Molecular Function: DNA binding; zinc ion binding; metal ion binding

Biological Process: negative regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; innate immune response; positive regulation of transcription factor activity