Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western Blot analysis in MDA-MB435 cell line lysates (35ug/lane) usingMBS6000508. DMC1 (arrow) was detected usingMBS6000508.)

Rabbit anti-Human DMC1 Polyclonal Antibody | anti-DMC1 antibody

DMC1, NT (DMC1, DMC1H, LIM15, Meiotic recombination protein DMC1/LIM15 homolog) (Azide free) (HRP)

Gene Names
DMC1; DMC1H; LIM15; dJ199H16.1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
DMC1; Polyclonal Antibody; NT (DMC1; DMC1H; LIM15; Meiotic recombination protein DMC1/LIM15 homolog) (Azide free) (HRP); Meiotic recombination protein DMC1/LIM15 homolog; anti-DMC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human DMC1.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-DMC1 antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human DMC1.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in MDA-MB435 cell line lysates (35ug/lane) usingMBS6000508. DMC1 (arrow) was detected usingMBS6000508.)

Western Blot (WB) (Western Blot analysis in MDA-MB435 cell line lysates (35ug/lane) usingMBS6000508. DMC1 (arrow) was detected usingMBS6000508.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human testis tissue usingMBS6000508, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of MBS6000508 for immunohistochemistry.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human testis tissue usingMBS6000508, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of MBS6000508 for immunohistochemistry.)

Testing Data

()

Testing Data ()
Product Categories/Family for anti-DMC1 antibody
References
1. Volodin, A.A. J. Biol. Chem. 284 (3), 1495-1504 (2009). 2. Hikiba, J.FEBS J. 276 (2), 457-465 (2009). 3. Hikiba, J. Nucleic Acids Res. 36 (12), 4181-4190 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,559 Da
NCBI Official Full Name
meiotic recombination protein DMC1/LIM15 homolog isoform 1
NCBI Official Synonym Full Names
DNA meiotic recombinase 1
NCBI Official Symbol
DMC1
NCBI Official Synonym Symbols
DMC1H; LIM15; dJ199H16.1
NCBI Protein Information
meiotic recombination protein DMC1/LIM15 homolog
UniProt Protein Name
Meiotic recombination protein DMC1/LIM15 homolog
UniProt Gene Name
DMC1
UniProt Synonym Gene Names
DMC1H; LIM15

NCBI Description

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Uniprot Description

May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.

Research Articles on DMC1

Similar Products

Product Notes

The DMC1 dmc1 (Catalog #AAA6292414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DMC1, NT (DMC1, DMC1H, LIM15, Meiotic recombination protein DMC1/LIM15 homolog) (Azide free) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DMC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DMC1 dmc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DMC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.