Rabbit anti-Human TRIM16 Polyclonal Antibody | anti-TRIM16 antibody

TRIM16 (Tripartite Motif-containing Protein 16, Estrogen-responsive B Box Protein, EBBP) APC

Cat. Num. AAA6397183

• Gene Names: TRIM16; EBBP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TRIM16; Polyclonal Antibody; TRIM16 (Tripartite Motif-containing Protein 16; Estrogen-responsive B Box Protein; EBBP) APC; anti-TRIM16 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TRIM16.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 2920

• Applicable Applications for anti-TRIM16 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full-length human TRIM16, aa1-564 (NP_006461.3).
• Immunogen Sequence: MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TRIM16 rabbit polyclonal antibody. Western Blot analysis of TRIM16 expression in HeLa.)

Western Blot (WB)

(Western Blot analysis of TRIM16 expression in transfected 293T cell line by TRIM16 polyclonal antibody. Lane 1: TRIM16 transfected lysate (64.0kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-TRIM16 antibody

The TRIM16 gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. TRIM16 contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth and differentiation. The TRIM16 gene is expressed in most tissues, and is more highly expressed in the fetus than in the corresponding adult tissues. TRIM16 may play a role in the regulation of keratinocyte differentiation.

Product Categories/Family for anti-TRIM16 antibody

Antibodies; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 48255912
• NCBI GeneID: 10626
• NCBI Accession #: NM_006470.3
• NCBI GenBank Nucleotide #: NM_006470.3
• NCBI Official Full Name: Homo sapiens tripartite motif containing 16 (TRIM16), mRNA
• NCBI Official Synonym Full Names: tripartite motif containing 16
• NCBI Official Symbol: TRIM16
• NCBI Official Synonym Symbols: EBBP
• NCBI Protein Information: tripartite motif-containing protein 16
• Protein Family: Tripartite motif-containing protein

NCBI Description

The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017]