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Western Blot (WB) (Western blot analysis of lysate from HL-60 cell line, using TREX2 Antibody (C-term). MBS9207723 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)

Rabbit anti-Human TREX2 Polyclonal Antibody | anti-TREX2 antibody

TREX2 Antibody (C-term)

Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TREX2; Polyclonal Antibody; TREX2 Antibody (C-term); Three prime repair exonuclease 2; 3'-5' exonuclease TREX2; anti-TREX2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TREX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 264-299 amino acids from the C-terminal region of human TREX2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
236
Applicable Applications for anti-TREX2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Function
Exonuclease with a preference for double-stranded DNA with mismatched 3'termini. May play a role in DNA repair.
Cellular Location
Nucleus
Tissue Location
Detected in heart , breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysate from HL-60 cell line, using TREX2 Antibody (C-term). MBS9207723 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)

Western Blot (WB) (Western blot analysis of lysate from HL-60 cell line, using TREX2 Antibody (C-term). MBS9207723 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Related Product Information for anti-TREX2 antibody
Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Product Categories/Family for anti-TREX2 antibody
References
Mazur D.J.,et al.J. Biol. Chem. 274:19655-19660(1999).
Mazur D.J.,et al.J. Biol. Chem. 276:14718-14727(2001).
Mazur D.J.,et al.J. Biol. Chem. 276:17022-17029(2001).
Perrino F.W.,et al.J. Biol. Chem. 280:15212-15218(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25922
NCBI Official Full Name
three prime repair exonuclease 2
NCBI Official Synonym Full Names
three prime repair exonuclease 2
NCBI Official Symbol
TREX2
NCBI Protein Information
three prime repair exonuclease 2
UniProt Protein Name
Three prime repair exonuclease 2
UniProt Gene Name
TREX2
UniProt Entry Name
TREX2_HUMAN

NCBI Description

This gene encodes a nuclear protein with 3' to 5' exonuclease activity. The encoded protein participates in double-stranded DNA break repair, and may interact with DNA polymerase delta. [provided by RefSeq, Nov 2012]

Uniprot Description

TREX2: Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair. Belongs to the exonuclease superfamily. TREX family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.11.2; Deoxyribonuclease; DNA repair, damage

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: nucleus

Molecular Function: protein homodimerization activity; nucleic acid binding; magnesium ion binding; 3'-5'-exodeoxyribonuclease activity; exodeoxyribonuclease III activity

Biological Process: DNA repair; DNA catabolic process, exonucleolytic; DNA metabolic process

Research Articles on TREX2

Similar Products

Product Notes

The TREX2 trex2 (Catalog #AAA9207723) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TREX2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TREX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TREX2 trex2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TREX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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