Western Blot (WB)
(TREML1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).)
Rabbit anti-Human, mouse TREML1 Polyclonal Antibody | anti-TREML1 antibody
TREML1 Antibody (C-term)
Western Blot (WB)
(TREML1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).)
Western Blot (WB)
(TREML1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).)
Western Blot (WB)
(TREML1 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).)
Western Blot (WB)
(TREML1 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).)
the single Ig variable (IgV) domain activating receptors TREM1 (MIM
605085) and TREM2 (MIM 605086), but it has distinct structural and
functional properties. TREML1 enhances calcium signaling in an SHP2
(PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed
12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by
OMIM].
Washington, A.V., et al. J. Clin. Invest. 119(6):1489-1501(2009)
Ford, J.W., et al. Curr. Opin. Immunol. 21(1):38-46(2009)
Nurden, A.T., et al. Thromb. Haemost. 100(1):45-51(2008)
Giomarelli, B., et al. Thromb. Haemost. 97(6):955-963(2007)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]
Uniprot Description
TREML1: Cell surface receptor that may play a role in the innate and adaptive immune response. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: cell surface; plasma membrane; integral to membrane
Molecular Function: protein binding
Biological Process: platelet activation; calcium-mediated signaling; innate immune response
Research Articles on TREML1
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Product Notes
The TREML1 treml1 (Catalog #AAA9206108) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 215-241. The TREML1 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TREML1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TREML1 treml1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TREML1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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