Rabbit TRAP1 Polyclonal Antibody | anti-TRAP1 antibody

TRAP1 Polyclonal Antibody

Cat. Num. AAA3011083

• Gene Names: TRAP1; HSP75; HSP 75; HSP90L; TRAP-1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: TRAP1; Polyclonal Antibody; TRAP1 Polyclonal Antibody; Heat shock protein 75; Heat shock protein 75 kDa; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; mitochondrial; TNF receptor associated protein 1; TNFR associated protein 1; TNFR-associated protein 1; TRAP 1; TRAP-1; Trap1; TRAP1_HUMAN; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; Tumor necrosis factor type 1 receptor-associated protein; anti-TRAP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TRAP1 polyclonal antibody detects endogenous levels of TRAP1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 704

• Applicable Applications for anti-TRAP1 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
• Immunogen: Recombinant full length Human TRAP1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of TRAP1 polyclonal antibody)

Immunohistochemistry (IHC)

(Immunohistochemistry (IHC) analysis of TRAP1 polyclonal antibody in paraffin-embedded Human Breast Cancer tissue.)

Immunofluorescence (IF)

(Immunofluorescence analysis of Hela cells, using TRAP1 polyclonal antibody)

Related Product Information for anti-TRAP1 antibody

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

• NCBI GI #: 67477458
• NCBI GeneID: 10131
• UniProt Accession #: Q12931
• Molecular Weight: ~80kDa
• NCBI Official Full Name: Heat shock protein 75 kDa, mitochondrial
• NCBI Official Synonym Full Names: TNF receptor associated protein 1
• NCBI Official Symbol: TRAP1
• NCBI Official Synonym Symbols: HSP75; HSP 75; HSP90L; TRAP-1
• NCBI Protein Information: heat shock protein 75 kDa, mitochondrial
• UniProt Protein Name: Heat shock protein 75 kDa, mitochondrial
• Protein Family: TNF receptor-associated protein
• UniProt Gene Name: TRAP1
• UniProt Synonym Gene Names: HSP75; HSP 75; TRAP-1
• UniProt Entry Name: TRAP1_HUMAN

NCBI Description

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Description

HSP75: Chaperone that expresses an ATPase activity. Belongs to the heat shock protein 90 family.

Protein type: Chaperone; Heat shock protein

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; membrane; mitochondrion; mitochondrial matrix; mitochondrial inner membrane; mitochondrial intermembrane space; lipid particle

Molecular Function: protein binding; unfolded protein binding; protein kinase binding; tumor necrosis factor receptor binding; ATP binding

Biological Process: response to stress