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Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Rabbit anti-Human Transmembrane Protease Polyclonal Antibody | anti-TMPRSS4 antibody

Polyclonal Antibody to Transmembrane Protease, Serine 4 (TMPRSS4)

Gene Names
TMPRSS4; CAPH2; MT-SP2; TMPRSS3
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Transmembrane Protease; Polyclonal Antibody; Polyclonal Antibody to Transmembrane Protease; Serine 4 (TMPRSS4); anti-TMPRSS4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against TMPRSS4. It has beenselected for its ability to recognize TMPRSS4 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Applicable Applications for anti-TMPRSS4 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Fragment
TMPRSS4 (Lys54~Leu437)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant TMPRSS4 (Lys54~Leu437) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2077198
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant protein.)

Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Bile duct cancer Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Bile duct cancer Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,786 Da
NCBI Official Full Name
transmembrane protease serine 4 isoform 3
NCBI Official Synonym Full Names
transmembrane protease, serine 4
NCBI Official Symbol
TMPRSS4
NCBI Official Synonym Symbols
CAPH2; MT-SP2; TMPRSS3
NCBI Protein Information
transmembrane protease serine 4
UniProt Protein Name
Transmembrane protease serine 4
UniProt Gene Name
TMPRSS4
UniProt Synonym Gene Names
TMPRSS3; CAPH2; MT-SP2

NCBI Description

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TMPRSS4: Probable protease. Seems to be capable of activating ENaC. Belongs to the peptidase S1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.-; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: integral component of membrane

Molecular Function: protein binding; scavenger receptor activity; serine-type endopeptidase activity

Biological Process: proteolysis; receptor-mediated endocytosis

Research Articles on TMPRSS4

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Product Notes

The TMPRSS4 tmprss4 (Catalog #AAA2027927) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Transmembrane Protease, Serine 4 (TMPRSS4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transmembrane Protease can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the TMPRSS4 tmprss4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transmembrane Protease, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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