Western Blot (WB)
(western blot All lanes:Transcriptional enhancer factor TEF-5 antibody at 2ug/ml Lane 1:HepG2 whole cell lysate Lane 2:mouse small intestine tissue Lane 3: 293t whole cell lysate Lane 4:Hela whole cell lysate secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size:49kDa observed band size:49kDa)
Rabbit anti-Human Transcriptional enhancer factor TEF-5 Polyclonal Antibody | anti-TEF-5 antibody
Rabbit anti-human Transcriptional enhancer factor TEF-5 polyclonal Antibody, FITC
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Western Blot (WB)
(western blot All lanes:Transcriptional enhancer factor TEF-5 antibody at 2ug/ml Lane 1:HepG2 whole cell lysate Lane 2:mouse small intestine tissue Lane 3: 293t whole cell lysate Lane 4:Hela whole cell lysate secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size:49kDa observed band size:49kDa)
Western Blot (WB)
(western blot All lanes:Transcriptional enhancer factor TEF-5 antibody at 2ug/ml Lane 1:HepG2 whole cell lysate Lane 2:mouse small intestine tissue Lane 3: 293t whole cell lysate Lane 4:Hela whole cell lysate secondary Goat polyclonal to rabbit at 1/10000 dilution predicted band size:49kDa observed band size:49kDa)
NCBI and Uniprot Product Information
NCBI Description
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. [provided by RefSeq, Jul 2008]
Uniprot Description
TEAD3: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 6p21.2
Cellular Component: nucleoplasm; transcription factor complex
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: asymmetric neuroblast division; female pregnancy; gene expression; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Research Articles on TEF-5
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Product Notes
The TEF-5 tead3 (Catalog #AAA1488241) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Transcriptional enhancer factor TEF-5 polyclonal Antibody, FITC reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transcriptional enhancer factor TEF-5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the TEF-5 tead3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transcriptional enhancer factor TEF-5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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