Rabbit Tra-2alpha Polyclonal Antibody | anti-Tra-2alpha antibody

Tra-2alpha (G241) Polyclonal Antibody

Cat. Num. AAA3002447

• Gene Names: TRA2A; AWMS1; HSU53209
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: Tra-2alpha; Polyclonal Antibody; Tra-2alpha (G241) Polyclonal Antibody; Transformer-2 protein homolog alpha; TRA-2 alpha; TRA2-alpha; Transformer-2 protein homolog A; TRA2A; anti-Tra-2alpha antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Tra-2alpha (G241) polyclonal antibody detects endogenous levels of Tra-2alpha protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 282

• Applicable Applications for anti-Tra-2alpha antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200
• Immunogen: Synthetic peptide, corresponding to amino acids 210-258 of Human Tra-2alpha.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of Tra-2alpha (G241) pAb at 1:1000 dilutionLane1:A549 whole cell lysate (20ug) Lane2:K562 whole cell lysate (20ug) Lane3:The Kidney tissue lysate of Mouse (40ug) Lane4:The Kidney tissue lysate of Rat (40ug))

Immunohistochemistry (IHC)

(Immunohistochemistry (IHC) analyzes of Tra-2alpha (G241) pAb in paraffin-embedded human brain tissue.)

Related Product Information for anti-Tra-2alpha antibody

TRA2A (Transformer 2 alpha) is a member of the transformer 2 homolog family and encodes a protein with two RS domains and an RRM (RNA recognition motif) domain. It is a sequence specific RNA binding protein which participates in the regulation of pre-mRNA splicing.

NCBI and Uniprot Product Information

• NCBI GI #: 9558733
• NCBI GeneID: 29896
• NCBI Accession #: NP_037425.1
• NCBI GenBank Nucleotide #: NP_037425.1
• UniProt Accession #: Q13595
• Molecular Weight: ~ 33kDa
• NCBI Official Full Name: transformer-2 protein homolog alpha isoform 1
• NCBI Official Synonym Full Names: transformer 2 alpha homolog
• NCBI Official Symbol: TRA2A
• NCBI Official Synonym Symbols: AWMS1; HSU53209
• NCBI Protein Information: transformer-2 protein homolog alpha
• UniProt Protein Name: Transformer-2 protein homolog alpha
• UniProt Gene Name: TRA2A
• UniProt Synonym Gene Names: TRA-2 alpha; TRA2-alpha
• UniProt Entry Name: TRA2A_HUMAN

NCBI Description

This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Uniprot Description

TRA2A: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 7p15.3

Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus

Molecular Function: nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome