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Western Blot (WB) (Western Blot analysis of HEPG2 cells using Tryptase-3 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000)

Rabbit anti-Human TPSD1 Polyclonal Antibody | anti-TPSD1 antibody

TPSD1 Antibody

Gene Names
TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TPSD1; Polyclonal Antibody; TPSD1 Antibody; Tryptase delta (EC 3.4.21.59) (Delta-tryptase) (HmMCP-3-like tryptase III) (Mast cell mMCP-7-like) (Tryptase-3); anti-TPSD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-TPSD1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA: 1:10000-20000
Immunogen
Synthesized peptide derived from Tryptase-3 at AA range: 51-100
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of HEPG2 cells using Tryptase-3 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000)

Western Blot (WB) (Western Blot analysis of HEPG2 cells using Tryptase-3 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:200)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,587 Da
NCBI Official Full Name
tryptase delta
NCBI Official Synonym Full Names
tryptase delta 1
NCBI Official Symbol
TPSD1
NCBI Official Synonym Symbols
MCP7L1; MMCP-7L; MCP7-LIKE
NCBI Protein Information
tryptase delta
UniProt Protein Name
Tryptase delta
Protein Family
UniProt Gene Name
TPSD1

NCBI Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008]

Uniprot Description

TPSD1: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Belongs to the peptidase S1 family. Tryptase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.21.59; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: proteolysis

Research Articles on TPSD1

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Product Notes

The TPSD1 tpsd1 (Catalog #AAA7122794) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TPSD1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TPSD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:10000-20000. Researchers should empirically determine the suitability of the TPSD1 tpsd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TPSD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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