Goat TPD52L2 / HD54 Polyclonal Antibody | anti-TPD52L2 antibody

Goat Polyclonal to Human TPD52L2 / HD54

Cat. Num. AAA247061

• Gene Names: TPD52L2; D54; TPD54
• Reactivity: Gibbon, Gorilla, Human, Orangutan; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: TPD52L2 / HD54; Polyclonal Antibody; Goat Polyclonal to Human TPD52L2 / HD54; Anti-TPD52L2 / HD54 Antibody (C-Terminus) IHC-plus; TPD52L2; D54; HCCR-binding protein 2; HD54; Tumor protein D52-like 2; Tumor protein D54; Human TPD52L2; anti-TPD52L2 antibody

• Host: Goat
• Reactivity: Gibbon, Gorilla, Human, Orangutan; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human TPD52L2. This antibody is expected to recognise all reported isoforms (NP_955392.1; NP_955393.1; NP_955394.1; NP_955395.1; NP_003279.2; NP_955391.1).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 206

• Applicable Applications for anti-TPD52L2 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA (1:16000), IHC-P (3.75 ug/ml), WB (1:16000, 0.1 - 0.3 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic peptide C-SGDKPLSDPAP from the C-terminus of human TPD52L2 (NP_955392.1; NP_955393.1; NP_955394.1; NP_955395.1; NP_003279.2; NP_955391.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Marmoset (91%).
• Immunogen Type: Synthetic peptide
• Immunogen: TPD52L2 / HD54 antibody was raised against synthetic peptide C-SGDKPLSDPAP from the C-terminus of human TPD52L2 (NP_955392.1; NP_955393.1; NP_955394.1; NP_955395.1; NP_003279.2; NP_955391.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Marmoset (91%); Bat, Water flea (82%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-TPD52L2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC)

(Anti-TPD52L2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC)

(Anti-TPD52L2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Western Blot (WB)

(Antibody (0.1 ug/ml) staining of Human Breast Cancer lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

• NCBI GI #: 40805860
• NCBI GeneID: 7165
• NCBI Accession #: NP_003279.2
• NCBI GenBank Nucleotide #: NM_003288.3
• UniProt Accession #: O43399; O43398; Q5JWU5; Q5JWU6; Q5JWU8; Q5U0E0; Q9H3Z6; B4DPJ6; E1P5G7
• Molecular Weight: 24,854 Da
• NCBI Official Full Name: tumor protein D54 isoform e
• NCBI Official Synonym Full Names: tumor protein D52-like 2
• NCBI Official Symbol: TPD52L2
• NCBI Official Synonym Symbols: D54; TPD54
• NCBI Protein Information: tumor protein D54; HCCR-binding protein 2
• UniProt Protein Name: Tumor protein D54
• Protein Family: Tumor protein
• UniProt Gene Name: TPD52L2
• UniProt Synonym Gene Names: hD54
• UniProt Entry Name: TPD54_HUMAN

NCBI Description

This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]

Uniprot Description

TPD52L2: a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells. Two alternatively sp[liced isoforms have been reported.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 20q13.2-q13.3

Cellular Component: perinuclear region of cytoplasm; cytoplasm

Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: regulation of cell proliferation