Immunohistochemistry (IHC)
(Sample Type: Mouse retinaApplication: ImmunofluorescenceSpecies+tissue/cell type: Mouse retinaPrimary antibody dilution: 1:200Secondary antibody: Goat anti-rabbit Alexafluor 568Secondary antibody dilution: 1:200)
Rabbit TPD52 Polyclonal Antibody | anti-TPD52 antibody
TPD52 antibody - middle region
Immunohistochemistry (IHC)
(Sample Type: Mouse retinaApplication: ImmunofluorescenceSpecies+tissue/cell type: Mouse retinaPrimary antibody dilution: 1:200Secondary antibody: Goat anti-rabbit Alexafluor 568Secondary antibody dilution: 1:200)
Immunohistochemistry (IHC)
(Sample Type: Mouse retinaApplication: ImmunofluorescenceSpecies+tissue/cell type: Mouse retinaPrimary antibody dilution: 1:200Secondary antibody: Goat anti-rabbit Alexafluor 568Secondary antibody dilution: 1:200)
Western Blot (WB)
(WB Suggested Anti-TPD52 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysateTPD52 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells)
Western Blot (WB)
(WB Suggested Anti-TPD52 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysateTPD52 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells)
Target Description: It belongs to the TPD52 family. Its exact function remains unknown.
NCBI and Uniprot Product Information
Uniprot Description
TPD52: a coiled-coil motif bearing hydrophilic protein known to be overexpressed in many human solid tumors of diverse cellular origins. May be associated with B cell differentiation. Increased expression is associated with increased proliferation and invasive capacity in different cell types. May negatively regulate ATM protein levels. Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary. Isoform 2 is expressed at lower levels in fetal brain and kidney than in adult brain and kidney. Eight isoforms of the human protein are produced by alternative splicing
Protein type: Endoplasmic reticulum; Calcium-binding
Chromosomal Location of Human Ortholog: 8q21.13
Cellular Component: perinuclear region of cytoplasm; endoplasmic reticulum; cytoplasm
Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity; calcium ion binding
Biological Process: anatomical structure morphogenesis; secretion; B cell differentiation; positive regulation of cell proliferation
Research Articles on TPD52
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Product Notes
The TPD52 tpd52 (Catalog #AAA3208950) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TPD52 antibody - middle region reacts with Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's TPD52 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the TPD52 tpd52 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: AGQKASAAFS SVGSVITKKL EDVKNSPTFK SFEEKVENLK SKVGGTKPAG. It is sometimes possible for the material contained within the vial of "TPD52, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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