Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Toll Like Receptor 6 (TLR6) Polyclonal Antibody | anti-TLR6 antibody
Polyclonal Antibody to Toll Like Receptor 6 (TLR6)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- ALAL IVGSMTPFSN ELESMVDYSN RNLTHVPKDL PPRTKALSLS QNSISELRMP DISFLSELRV LRLSHNRIRS LDFHVFLFNQ DLEYLDVSHN RLQNISCCPM ASLRHLDLSF NDFDVLPVCK EFGNLTKLTF LGLSAAKFRQ LDLLPVAHLH LSCILLDLVS YHIKGGETES LQIPNTTVLH LVFHPNSLFS
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
NCBI and Uniprot Product Information
Uniprot Description
TLR6: Participates in the innate immune response to Gram- positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. Belongs to the Toll-like receptor family.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 5 C3.1|5 33.54 cM
Cellular Component: cytoplasmic vesicle; Golgi apparatus; integral component of membrane; integral component of plasma membrane; intracellular; membrane; membrane raft; plasma membrane; receptor complex
Molecular Function: diacyl lipopeptide binding; identical protein binding; protein heterodimerization activity; receptor binding; transmembrane receptor activity
Biological Process: cell activation; defense response to bacterium; detection of diacyl bacterial lipopeptide; immune system process; inflammatory response; innate immune response; interleukin-1 beta secretion; microglial cell activation; MyD88-dependent toll-like receptor signaling pathway; negative regulation of toll-like receptor 2 signaling pathway; nitric oxide metabolic process; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of inflammatory response; positive regulation of interleukin-12 biosynthetic process; positive regulation of interleukin-6 biosynthetic process; positive regulation of JUN kinase activity; positive regulation of macrophage activation; positive regulation of NF-kappaB transcription factor activity; positive regulation of nitric oxide biosynthetic process; regulation of cytokine secretion; response to bacterial lipoprotein; signal transduction; T-helper 1 type immune response; toll-like receptor 6 signaling pathway; toll-like receptor signaling pathway
Research Articles on TLR6
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Product Notes
The TLR6 tlr6 (Catalog #AAA2014339) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Toll Like Receptor 6 (TLR6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Toll Like Receptor 6 (TLR6) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the TLR6 tlr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- ALAL IVGSMTPFSN ELESMVDYSN RNLTHVPKDL PPRTKALSLS QNSISELRMP DISFLSELRV LRLSHNRIRS LDFHVFLFNQ DLEYLDVSHN RLQNISCCPM ASLRHLDLSF NDFDVLPVCK EFGNLTKLTF LGLSAAKFRQ LDLLPVAHLH LSCILLDLVS YHIKGGETES LQIPNTTVLH LVFHPNSLFS. It is sometimes possible for the material contained within the vial of "Toll Like Receptor 6 (TLR6), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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