Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using BCCIP antibody at 1:200 dilution.)
Rabbit TOK1 alpha Polyclonal Antibody | anti-TOK1 alpha antibody
TOK1 alpha antibody
Applications
Immunofluorescence, Immunocytochemistry, Western Blot
Purity
TOK1 alpha antibody was purified by antigen-affinity chromatography
Synonyms
TOK1 alpha; Polyclonal Antibody; TOK1 alpha antibody; Polyclonal TOK1 alpha; Anti-TOK1 alpha; TOK-1beta; BCCIPbeta; TOK-1; TOK-1alpha; TOK1; BCCIP; protein TOK-1; BRCA2 and Cip1/p21 interacting protein; BRCA2 and CDKN1A-interacting protein; cdk inhibitor p21 binding protein; anti-TOK1 alpha antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TOK1 alpha antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-TOK1 alpha antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Biological Significance
This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression.
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using BCCIP antibody at 1:200 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using BCCIP antibody at 1:200 dilution.)
Western Blot (WB)
(Western blot analysis of 30 ug of whole cell lysate (A: A431; B: Hela) using a 10 % SDS PAGE gel and TOK1 alpha antibody at a dilution of 1:1000)
Western Blot (WB)
(Western blot analysis of 30 ug of whole cell lysate (A: A431; B: Hela) using a 10 % SDS PAGE gel and TOK1 alpha antibody at a dilution of 1:1000)
Related Product Information for anti-TOK1 alpha antibody
Affinity purified Rabbit polyclonal TOK1 alpha antibody
Product Categories/Family for anti-TOK1 alpha antibody
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Product Notes
The TOK1 alpha (Catalog #AAA837598) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TOK1 alpha can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB). Researchers should empirically determine the suitability of the TOK1 alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOK1 alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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