Western Blot (WB)
(Western blot analysis of TOB2 in human heart lysate in the 1) absence and 2) presence of immunizing peptide using at 0.5ug/ml.)
Rabbit TOB2 Polyclonal Antibody | anti-TOB2 antibody
TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2)
Gene Names
TOB2; TOB4; TOBL; TROB2
Reactivity
Bovine, Canine, Chicken, Equine, Human, Mouse
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
TOB2; Polyclonal Antibody; TOB2 (Protein Tob2; Transducer of erbB-2 2; Protein Tob4; KIAA1663; TOB4; TOBL; TROB2); Anti -TOB2 (Protein Tob2; anti-TOB2 antibody
Host
Rabbit
Reactivity
Bovine, Canine, Chicken, Equine, Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human TOB2. Species Crossreactivity
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Applicable Applications for anti-TOB2 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
Synthetic peptide corresponding to aa50-100 of human TOB2.
Positive Control
Human heart lysate
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western blot analysis of TOB2 in human heart lysate in the 1) absence and 2) presence of immunizing peptide using at 0.5ug/ml.)
Western Blot (WB)
(Western blot analysis of TOB2 in human heart lysate in the 1) absence and 2) presence of immunizing peptide using at 0.5ug/ml.)
Related Product Information for anti-TOB2 antibody
TOB2 is a 344aa rich novel member of the Tob:BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG:Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0:G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.
Product Categories/Family for anti-TOB2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
36,632 Da
NCBI Official Full Name
TOB2
NCBI Official Synonym Full Names
transducer of ERBB2, 2
NCBI Official Symbol
TOB2
NCBI Official Synonym Symbols
TOB4; TOBL; TROB2
NCBI Protein Information
protein Tob2; protein Tob4; transducer of erbB-2 2
UniProt Protein Name
Protein Tob2
Protein Family
UniProt Gene Name
TOB2
UniProt Synonym Gene Names
KIAA1663; TOB4; TROB2
UniProt Entry Name
TOB2_HUMAN
NCBI Description
TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004]
Uniprot Description
Function: Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
Subunit structure: Associates with CAF1.
Subcellular location: Cytoplasm.
Tissue specificity: Ubiquitous.
Sequence similarities: Belongs to the BTG family.
Sequence caution: The sequence BAB33333.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on TOB2
Similar Products
Product Notes
The TOB2 tob2 (Catalog #AAA646978) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TOB2 (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TOBL, TROB2) reacts with Bovine, Canine, Chicken, Equine, Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TOB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the TOB2 tob2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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