Rabbit anti-Human, Mouse TNFRSF17 Polyclonal Antibody | anti-TNFRSF17 antibody

TNFRSF17 Antibody

Cat. Num. AAA7127944

• Gene Names: TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: TNFRSF17; Polyclonal Antibody; TNFRSF17 Antibody; Tumor necrosis factor receptor superfamily; member 17; anti-TNFRSF17 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-TNFRSF17 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:1000-1:2000; WB: 1:200-1:1000; IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human TNFRSF17
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using MBS7127944(TNFRSF17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7127944(TNFRSF17 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane: Mouse skeletal muscle tissue, Primary antibody: MBS7127944(TNFRSF17 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds)

Product Categories/Family for anti-TNFRSF17 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 23238192
• NCBI GeneID: 608
• NCBI Accession #: NP_001183.2
• NCBI GenBank Nucleotide #: NM_001192.2
• UniProt Accession #: Q02223; Q2TQ40
• Molecular Weight: 14,843 Da
• NCBI Official Full Name: tumor necrosis factor receptor superfamily member 17
• NCBI Official Synonym Full Names: tumor necrosis factor receptor superfamily, member 17
• NCBI Official Symbol: TNFRSF17
• NCBI Official Synonym Symbols: BCM; BCMA; CD269; TNFRSF13A
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 17
• Protein Family: Tumor necrosis factor receptor superfamily
• UniProt Gene Name: TNFRSF17
• UniProt Synonym Gene Names: BCM; BCMA
• UniProt Entry Name: TNR17_HUMAN

NCBI Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]

Uniprot Description

TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.

Protein type: Membrane protein, integral; Oncoprotein; Receptor, misc.

Chromosomal Location of Human Ortholog: 16p13.1

Cellular Component: integral to membrane; plasma membrane; endomembrane system

Molecular Function: receptor activity

Biological Process: cell proliferation; immune system process; multicellular organismal development; signal transduction