Western Blot/Blotting
(Western blot analysis of TNFRSF14 in Raji cell lysate with TNFRSF14 antibody at 2 g/ml in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human TNFRSF14 CT (Tumor necrosis factor receptor superfamily 14) Polyclonal Antibody | anti-TNFRSF14 antibody
TNFRSF14 CT (Tumor necrosis factor receptor superfamily 14)
Western Blot/Blotting
(Western blot analysis of TNFRSF14 in Raji cell lysate with TNFRSF14 antibody at 2 g/ml in (A) the absence and (B) the presence of blocking peptide.)
Western Blot/Blotting
(Western blot analysis of TNFRSF14 in Raji cell lysate with TNFRSF14 antibody at 2 g/ml in (A) the absence and (B) the presence of blocking peptide.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. Ref.1
Subunit structure: Interacts with TRAF2, TRAF3 and TRAF5. Interacts with herpes simplex virus 1 (HHV-1) and herpes simplex virus 1 (HHV-2) envelope glycoprotein D; functions as an entry receptor for these viruses. Ref.12 Ref.13 Ref.14
Subcellular location: Membrane; Single-pass type I membrane protein
Probable.
Tissue specificity: Widely expressed, with the highest expression in lung, spleen and thymus.
Post-translational modification: N-glycosylated. Ref.16
Sequence similarities: Contains 3 TNFR-Cys repeats.
Research Articles on TNFRSF14
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Product Notes
The TNFRSF14 tnfrsf14 (Catalog #AAA395862) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNFRSF14 CT (Tumor necrosis factor receptor superfamily 14) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNFRSF14 CT (Tumor necrosis factor receptor superfamily 14) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TNFRSF14 tnfrsf14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFRSF14 CT (Tumor necrosis factor receptor superfamily 14), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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