Rabbit TNFAIP8L2 Polyclonal Antibody | anti-TNFAIP8L2 antibody

TNFAIP8L2 Antibody (N-term)

Cat. Num. AAA9212382

• Gene Names: TNFAIP8L2; TIPE2
• Reactivity: Mouse (Predicted Reactivity: Rabbit)
• Applications: Western Blot, ELISA
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: TNFAIP8L2; Polyclonal Antibody; TNFAIP8L2 Antibody (N-term); Tumor necrosis factor alpha-induced protein 8-like protein 2; TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2; Inflammation factor protein 20; anti-TNFAIP8L2 antibody

• Host: Rabbit
• Reactivity: Mouse (Predicted Reactivity: Rabbit)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This TNFAIP8L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human TNFAIP8L2.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.37 (varies by lot)
• Sequence Positions: 29-58
• Sequence Length: 184

• Applicable Applications for anti-TNFAIP8L2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB~~1:1000
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(TNFAIP8L2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the TNFAIP8L2 antibody detected the TNFAIP8L2 protein (arrow).)

Related Product Information for anti-TNFAIP8L2 antibody

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).

References

Zhang, G., et al. Mol. Immunol. 47(15):2435-2442(2010)

NCBI and Uniprot Product Information

• NCBI GI #: 157389001
• NCBI GeneID: 79626
• NCBI Accession #: NP_078851.2
• NCBI GenBank Nucleotide #: NM_024575.4
• UniProt Accession #: Q6P589; Q6I9Y0; Q9H2H7; Q9H5G2
• Molecular Weight: 20556
• NCBI Official Full Name: tumor necrosis factor alpha-induced protein 8-like protein 2
• NCBI Official Synonym Full Names: tumor necrosis factor, alpha-induced protein 8-like 2
• NCBI Official Symbol: TNFAIP8L2
• NCBI Official Synonym Symbols: TIPE2
• NCBI Protein Information: tumor necrosis factor alpha-induced protein 8-like protein 2
• UniProt Protein Name: Tumor necrosis factor alpha-induced protein 8-like protein 2
• Protein Family: Tumor necrosis factor alpha-induced protein 8-like protein
• UniProt Gene Name: TNFAIP8L2
• UniProt Synonym Gene Names: TIPE2; TNF alpha-induced protein 8-like protein 2; TNFAIP8-like protein 2
• UniProt Entry Name: TP8L2_HUMAN

Uniprot Description

TNFAIP8L2: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis. Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: negative regulation of inflammatory response; innate immune response; negative regulation of T cell activation