Western Blot (WB)
(WB Suggested Anti-TMX1 AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Rabbit TMX1 Polyclonal Antibody | anti-TMX1 antibody
TMX1 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-TMX1 AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-TMX1 AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Target Description: TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]
Uniprot Description
TXNDC1: May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 14q22.1
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; nucleolus; integral to membrane
Molecular Function: disulfide oxidoreductase activity; protein disulfide isomerase activity
Biological Process: protein folding; cell redox homeostasis
Research Articles on TMX1
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Product Notes
The TMX1 tmx1 (Catalog #AAA3215808) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMX1 antibody - C-terminal region reacts with Cow, Dog, Goat, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's TMX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TMX1 tmx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: YPSKKLLSES AQPLKKVEEE QEADEEDVSE EEAESKEGTN KDFPQNAIRQ. It is sometimes possible for the material contained within the vial of "TMX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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