Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20.)
Rabbit anti-Human TMPRSS11B Polyclonal Antibody | anti-TMPRSS11B antibody
TMPRSS11B Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
TMPRSS11B; Polyclonal Antibody; TMPRSS11B Antibody; anti-TMPRSS11B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TMPRSS11B protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.2 mg/ml (varies by lot)
Sequence Length
416
Applicable Applications for anti-TMPRSS11B antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:10-1:50
Immunogen Type
Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human transmembrane protease, serine 11B
Target Name
TMPRSS11B
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/20.)
Related Product Information for anti-TMPRSS11B antibody
TMPRSS11B (transmembrane protease serine 11B), also known as airway trypsin-like protease 5, is a 416 amino acid single-pass type II membrane protein that belongs to the peptidase S1 family and contains one peptidase S1 domain and one SEA domain. The gene that encodes TMPRSS11B consists of over 19,000 bases and maps to human chromosome 4q13.2. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Product Categories/Family for anti-TMPRSS11B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,337 Da
NCBI Official Full Name
transmembrane protease serine 11B
NCBI Official Synonym Full Names
transmembrane protease, serine 11B
NCBI Official Symbol
TMPRSS11B
NCBI Protein Information
transmembrane protease serine 11B
UniProt Protein Name
Transmembrane protease serine 11B
Protein Family
UniProt Gene Name
TMPRSS11B
UniProt Synonym Gene Names
HATL5
UniProt Entry Name
TM11B_HUMAN
Uniprot Description
TMPRSS11B: Probable serine protease. Belongs to the peptidase S1 family.
Protein type: Membrane protein, integral; EC 3.4.21.-; Protease
Chromosomal Location of Human Ortholog: 4q13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
Research Articles on TMPRSS11B
Similar Products
Product Notes
The TMPRSS11B tmprss11b (Catalog #AAA9407703) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMPRSS11B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMPRSS11B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the TMPRSS11B tmprss11b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMPRSS11B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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