Mouse cGMP Monoclonal Antibody | anti-cGMP antibody

Anti-cGMP Antibody

Cat. Num. AAA847158

• Applications: ELISA
• Purity: Protein A purification
• Synonyms: cGMP; Monoclonal Antibody; Anti-cGMP Antibody; Cyclic GMP; Cyclic guanosine monophosphate; anti-cGMP antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG2a, kappa
• Clone Number: 2F11E10
• Specificity: Monoclonal antibody to detect cGMP. The specificity of the antibody is defined as the ratio of antigen concentration to cross-reactant concentration at 50% inhibition of maximum binding.
• Purity/Purification: Protein A purification
• Form/Format: Colorless liquid. PBS, pH7.4, containing 0.02% sodium azide

• Applicable Applications for anti-cGMP antibody: ELISA (EIA)
• Application Notes: ELISA: 0.04-0.1ug/ml
• Immunogen: 3', 5'-cyclic GMP-8-KLH
• Preparation and Storage: Store at -20 degree C; The antibody solution should be gently mixed before use.; Shelf life: ~12 months

ELISA (EIA)

Related Product Information for anti-cGMP antibody

Guanosine 3, 5-cyclic monophosphate (cyclic GMP; cGMP) acts as a secondary messenger much like cyclic AMP. It is generally known to activate intracellular protein kinases in response to the binding of membrane-impermeable peptide hormones to the cell surface. cGMP synthesis is catalyzed by guanylate cyclase (GC), which converts GTP to cGMP. Membrane-bound GC is activated by peptide hormones such as atrial natriuretic factor, while soluble GC is typically activated by nitric oxide (NO) to stimulate cGMP synthesis. cGMP is also a common regulator of ion channel conductance, glycogenolysis, and cellular apoptosis. It also relaxes smooth muscle tissues. The roles of cGMP and cAMP may be linked, as evidenced by the fact that some cellular functions are controlled bi-directionally by both cAMP and cGMP. Some functions are stimulated by cGMP and suppressed by cAMP and vice versa.