Western Blot (WB)
(TMEM16C antibody (MBS5302897) used at 1 ug/ml to detect target protein.)
Rabbit TMEM16C Polyclonal Antibody | anti-TMEM16C antibody
TMEM16C antibody
Western Blot (WB)
(TMEM16C antibody (MBS5302897) used at 1 ug/ml to detect target protein.)
Western Blot (WB)
(TMEM16C antibody (MBS5302897) used at 1 ug/ml to detect target protein.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Uniprot Description
ANO3: May act as a calcium-activated chloride channel. Belongs to the anoctamin family.
Protein type: Transporter; Transporter, ion channel; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11p14.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: phospholipid scramblase activity; intracellular calcium activated chloride channel activity
Biological Process: lipid transport; transmembrane transport
Disease: Dystonia 24
Research Articles on TMEM16C
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Product Notes
The TMEM16C ano3 (Catalog #AAA5302897) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM16C antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM16C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1 ug/ml. Researchers should empirically determine the suitability of the TMEM16C ano3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM16C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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