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Western Blot (WB) (All lanes : Anti-TMEM158 Antibody (C-Term) at 1:2000 dilutionLane 1: K562 whole cell lysateLane 2: THP-1 whole cell lysateLane 3: HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit TMEM158 Polyclonal Antibody | anti-TMEM158 antibody

TMEM158 Antibody (C-Term)

Gene Names
TMEM158; BBP; RIS1; p40BBP
Reactivity
Human
Predicted: Bovine , Mouse, Rat
Applications
Western Blot, ELISA
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
TMEM158; Polyclonal Antibody; TMEM158 Antibody (C-Term); Purified Rabbit Polyclonal Antibody (Pab); Transmembrane protein 158; 40 kDa BINP-binding protein; p40BBP; Ras-induced senescence protein 1; HBBP; RIS1; anti-TMEM158 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Bovine , Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TMEM158 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from human TMEM158.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
300
Applicable Applications for anti-TMEM158 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:2000
Cellular Location
Membrane; Multi-pass membrane protein
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-TMEM158 Antibody (C-Term) at 1:2000 dilutionLane 1: K562 whole cell lysateLane 2: THP-1 whole cell lysateLane 3: HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-TMEM158 Antibody (C-Term) at 1:2000 dilutionLane 1: K562 whole cell lysateLane 2: THP-1 whole cell lysateLane 3: HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-TMEM158 antibody
Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide.
Product Categories/Family for anti-TMEM158 antibody
References
Barradas M.,et al.Exp. Cell Res. 273:127-137(2002). Hama T.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases. Muzny D.M.,et al.Nature 440:1194-1198(2006). Bechtel S.,et al.BMC Genomics 8:399-399(2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30404
NCBI Official Full Name
transmembrane protein 158
NCBI Official Synonym Full Names
transmembrane protein 158 (gene/pseudogene)
NCBI Official Symbol
TMEM158
NCBI Official Synonym Symbols
BBP; RIS1; p40BBP
NCBI Protein Information
transmembrane protein 158
UniProt Protein Name
Transmembrane protein 158
Protein Family
UniProt Gene Name
TMEM158
UniProt Synonym Gene Names
HBBP; RIS1; p40BBP
UniProt Entry Name
TM158_HUMAN

NCBI Description

Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]

Uniprot Description

TMEM158: Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide. Belongs to the TMEM158 family. Up-regulated during Ras-induced senesence. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: integral to membrane

Molecular Function: peptide binding

Research Articles on TMEM158

Similar Products

Product Notes

The TMEM158 tmem158 (Catalog #AAA9216974) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM158 Antibody (C-Term) reacts with Human Predicted: Bovine, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM158 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:2000. Researchers should empirically determine the suitability of the TMEM158 tmem158 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM158, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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