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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using MBS7126544(TMED1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200))

Rabbit TMED1 Polyclonal Antibody | anti-TMED1 antibody

TMED1 Antibody

Gene Names
TMED1; Tp24; Il1rl1l; IL1RL1LG
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
TMED1; Polyclonal Antibody; TMED1 Antibody; Transmembrane emp24 protein Transport domain containing 1; anti-TMED1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-TMED1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:5000
WB: 1:500-1:2000
IHC: 1:25-1:100
Immunogen
Fusion protein of human TMED1
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using MBS7126544(TMED1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using MBS7126544(TMED1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7126544(TMED1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7126544(TMED1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200))

SDS-Page

(Gel: 12%SDS-PAGE,Lysate: 40 ug,Lane 1-4: A172 cells, 231 cells, Human normal stomach tissue, Hela cells,Primary antibody: MBS7126544(TMED1 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds)

SDS-Page (Gel: 12%SDS-PAGE,Lysate: 40 ug,Lane 1-4: A172 cells, 231 cells, Human normal stomach tissue, Hela cells,Primary antibody: MBS7126544(TMED1 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 40 seconds)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,206 Da
NCBI Official Full Name
transmembrane emp24 domain-containing protein 1
NCBI Official Synonym Full Names
transmembrane emp24 protein transport domain containing 1
NCBI Official Symbol
TMED1
NCBI Official Synonym Symbols
Tp24; Il1rl1l; IL1RL1LG
NCBI Protein Information
transmembrane emp24 domain-containing protein 1; IL1RL1-binding protein; p24 family protein gamma-1; interleukin 1 receptor-like 1 ligand; putative T1/ST2 receptor-binding protein
UniProt Protein Name
Transmembrane emp24 domain-containing protein 1
UniProt Gene Name
TMED1
UniProt Synonym Gene Names
IL1RL1L; IL1RL1LG; Tp24; p24gamma1
UniProt Entry Name
TMED1_HUMAN

NCBI Description

This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Uniprot Description

TMED1: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Belongs to the EMP24/GP25L family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; endoplasmic reticulum; plasma membrane; integral to membrane; ER-Golgi intermediate compartment

Molecular Function: protein binding; receptor binding

Biological Process: protein transport; cell-cell signaling; signal transduction

Research Articles on TMED1

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Product Notes

The TMED1 tmed1 (Catalog #AAA7126544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMED1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMED1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the TMED1 tmed1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMED1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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