Western Blot (WB)
(Western blot analysis of Mouse TLR6 Antibody (C-term) in K562 cell line lysates (35ug/lane). TLR6 (arrow) was detected using the purified Pab.)
Rabbit anti-Human, mouse TLR6 Polyclonal Antibody | anti-Tlr6 antibody
Mouse TLR6 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of Mouse TLR6 Antibody (C-term) in K562 cell line lysates (35ug/lane). TLR6 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of Mouse TLR6 Antibody (C-term) in K562 cell line lysates (35ug/lane). TLR6 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Mouse TLR6 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Mouse TLR6 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Takeuchi, O., et al., Gene 231 (1-2), 59-65 (1999).
NCBI and Uniprot Product Information
Uniprot Description
TLR6: Participates in the innate immune response to Gram- positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. Belongs to the Toll-like receptor family.
Protein type: Receptor, misc.; Membrane protein, integral
Cellular Component: membrane; plasma membrane; integral to membrane; cytoplasmic vesicle
Molecular Function: transmembrane receptor activity; protein heterodimerization activity; diacylated lipoprotein binding
Biological Process: positive regulation of JNK activity; regulation of cytokine secretion; T-helper 1 type immune response; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; detection of diacylated bacterial lipoprotein; positive regulation of interleukin-6 biosynthetic process; microglial cell activation; signal transduction; nitric oxide metabolic process; MyD88-dependent toll-like receptor signaling pathway; positive regulation of interleukin-12 biosynthetic process; toll-like receptor 6 signaling pathway; toll-like receptor signaling pathway; innate immune response; immune response; response to bacterial lipoprotein; inflammatory response
Research Articles on Tlr6
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Product Notes
The Tlr6 tlr6 (Catalog #AAA9213258) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 722-753. The Mouse TLR6 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TLR6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Tlr6 tlr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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