Rabbit anti-Human TLK2 Polyclonal Antibody | anti-TLK2 antibody

TLK2, ID (Serine/Threonine-protein Kinase Tousled-like 2, Tousled-like Kinase 2, PKU-alpha) (Azide free) (HRP)

Cat. Num. AAA6502832

• Gene Names: TLK2; HsHPK; MRD57; PKU-ALPHA
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein G Affinity Chromatography.
• Synonyms: TLK2; Polyclonal Antibody; ID (Serine/Threonine-protein Kinase Tousled-like 2; Tousled-like Kinase 2; PKU-alpha) (Azide free) (HRP); anti-TLK2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TLK2.
• Purity/Purification: Purified by Protein G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Sequence Length: 772

• Applicable Applications for anti-TLK2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-1:500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the center region of human TLK2 (KLH).
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-TLK2 Antibody (Center) in mouse testis tissue lysates (35ug/lane).TLK2(arrow) was detected using the purified Pab.)

Western Blot (WB)

(TLK2 Antibody (K155) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the TLK2 antibody detected the TLK2 protein (arrow).)

Product Categories/Family for anti-TLK2 antibody

Antibodies; Protein Kinases

References

1. Groth, A., et al., EMBO J. 22(7):1676-1687 (2003). 2. Strausberg, R.L., et al., Proc. Natl. Acad. Sci. USA 99(26):16899-16903 (2002). 3. Sillje, H.H., et al., EMBO J. 18(20):5691-5702 (1999). 4. Yamakawa, A., et al., Gene 202(1-2), 193-201 (1997).

NCBI and Uniprot Product Information

• NCBI GI #: 34222826
• NCBI GeneID: 11011
• UniProt Accession #: Q9UKI7; Q86UE8
• Molecular Weight: 87.66
• NCBI Official Full Name: Serine/threonine-protein kinase tousled-like 2
• NCBI Official Synonym Full Names: tousled like kinase 2
• NCBI Official Symbol: TLK2
• NCBI Official Synonym Symbols: HsHPK; MRD57; PKU-ALPHA
• NCBI Protein Information: serine/threonine-protein kinase tousled-like 2
• Protein Family: Serine/threonine-protein kinase tousled

NCBI Description

This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]