Rabbit anti-Human TK1 / TK / Thymidine Kinase Polyclonal Antibody | anti-TK1 antibody

Rabbit Polyclonal to Human TK1 / TK / Thymidine Kinase

Cat. Num. AAA241732

• Gene Names: TK1; TK2
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: TK1 / TK / Thymidine Kinase; Polyclonal Antibody; Rabbit Polyclonal to Human TK1 / TK / Thymidine Kinase; Anti-TK1 / TK / Thymidine Kinase Antibody (N-Terminus) IHC-plus; TK1; Spleen tyrosine kinase; Thymidine kinase 1; soluble; Thymidine Kinase 1; Thymidine kinase; cytosolic; Thymidine kinase-1; TK; Human TK1; Thymidine Kinase; anti-TK1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: synthetic peptide corresponding to N-terminal residues of human TK1 (Thymidine kinase, cytosolic)
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.01% sodium azide, 50% glycerol.
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 234

• Applicable Applications for anti-TK1 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA (1 ug/ml), IHC-P (20 ug/ml), WB (1 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human TK1 / Thymidine Kinase-1.
• Immunogen Type: Synthetic peptide
• Immunogen: TK1 / TK / Thymidine Kinase antibody was raised against synthetic peptide from human TK1 / Thymidine Kinase-1.
• Antigen Modification: N-Terminus
• Preparation and Storage: +4 degree C or -20 degree C, Avoid repeated freezing and thawing.

Immunohistochemistry (IHC)

(Anti-TK1 / Thymidine Kinase-1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 164698438
• NCBI GeneID: 7083
• NCBI Accession #: NP_003249.3
• NCBI GenBank Nucleotide #: NM_003258.4
• UniProt Accession #: P04183; Q969V0; Q9UMG9; B2RC58
• Molecular Weight: 25,469 Da
• NCBI Official Full Name: thymidine kinase, cytosolic
• NCBI Official Synonym Full Names: thymidine kinase 1, soluble
• NCBI Official Symbol: TK1
• NCBI Official Synonym Symbols: TK2
• NCBI Protein Information: thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform
• UniProt Protein Name: Thymidine kinase, cytosolic
• Protein Family: Thymidine kinase
• UniProt Gene Name: TK1
• UniProt Entry Name: KITH_HUMAN

Uniprot Description

TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.

Protein type: Nucleotide Metabolism - pyrimidine; EC 2.7.1.21; Xenobiotic Metabolism - drug metabolism - other enzymes; Kinase, other

Chromosomal Location of Human Ortholog: 17q23.2-q25.3

Cellular Component: cytosol

Molecular Function: identical protein binding; nucleoside kinase activity; zinc ion binding; thymidine kinase activity; ATP binding

Biological Process: response to nutrient levels; skeletal muscle cell proliferation; nucleobase, nucleoside and nucleotide metabolic process; response to toxin; liver development; fetal process involved in parturition; deoxyribonucleoside monophosphate biosynthetic process; protein homotetramerization; response to cortisol stimulus; gut development; pyrimidine base metabolic process; response to copper ion; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; pyrimidine nucleoside salvage; thymidine metabolic process; phosphorylation