Rabbit TK1 Polyclonal Antibody | anti-TK1 antibody

TK1 Rabbit Polyclonal

Cat. Num. AAA7604951

• Gene Names: TK1; TK2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: TK1; Polyclonal Antibody; TK1 Rabbit Polyclonal; anti-TK1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 234

• Applicable Applications for anti-TK1 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: Thymidine kinase 1, soluble
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using MBS7604951 (TK1 Antibody) at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of Hela cells, using TK1 antibody MBS7604951 (TK1 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red) .)

Immunoprecipitation (IP)

(IP Result of anti-TK1 (IP: MBS7604951, 4ug; Detection: MBS7604951 1:500) with HEK-293 cells lysate 2000ug.)

Western Blot (WB)

(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS7604951 (TK1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 164698438
• NCBI GeneID: 7083
• NCBI Accession #: NP_003249.3
• NCBI GenBank Nucleotide #: NM_003258.4
• Molecular Weight: 25,469 Da
• NCBI Official Full Name: thymidine kinase, cytosolic
• NCBI Official Synonym Full Names: thymidine kinase 1
• NCBI Official Symbol: TK1
• NCBI Official Synonym Symbols: TK2
• NCBI Protein Information: thymidine kinase, cytosolic
• UniProt Protein Name: Thymidine kinase, cytosolic
• Protein Family: Thymidine kinase
• UniProt Gene Name: TK1
• UniProt Entry Name: KITH_HUMAN

Uniprot Description

TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells.

Protein type: Kinase, other; Nucleotide Metabolism - pyrimidine; EC 2.7.1.21; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 17q23.2-q25.3

Cellular Component: cytosol

Molecular Function: ATP binding; identical protein binding; nucleoside kinase activity; protein binding; thymidine kinase activity; zinc ion binding

Biological Process: deoxyribonucleoside monophosphate biosynthetic process; DNA metabolic process; fetal process involved in parturition; gut development; liver development; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide biosynthetic process; phosphorylation; protein homotetramerization; pyrimidine nucleoside salvage; response to copper ion; response to cortisol stimulus; response to nutrient levels; response to toxin; skeletal muscle cell proliferation; thymidine metabolic process