Western Blot (WB)
(TIMM50 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TIMM50 antibody detected the TIMM50 protein (arrow).)
Rabbit anti-Human TIMM50 Polyclonal Antibody | anti-TIMM50 antibody
TIMM50 Antibody (N-term)
Western Blot (WB)
(TIMM50 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TIMM50 antibody detected the TIMM50 protein (arrow).)
Western Blot (WB)
(TIMM50 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TIMM50 antibody detected the TIMM50 protein (arrow).)
Xu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :
Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)
Yuryev, A., et al. Genomics 81(2):112-125(2003)
Yamamoto, H., et al. Cell 111(4):519-528(2002)
NCBI and Uniprot Product Information
Uniprot Description
TIMM50: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body. Belongs to the TIM50 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Mitochondrial; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: nucleoplasm; mitochondrion; mitochondrial inner membrane; integral to membrane; nuclear speck; mitochondrial inner membrane presequence translocase complex
Molecular Function: ribonucleoprotein binding; protein binding; RNA binding; interleukin-2 receptor binding; protein tyrosine phosphatase activity; protein serine/threonine phosphatase activity; phosphoprotein phosphatase activity
Biological Process: release of cytochrome c from mitochondria; cellular protein metabolic process; mitochondrial membrane organization and biogenesis; protein amino acid dephosphorylation; protein targeting to mitochondrion
Research Articles on TIMM50
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Product Notes
The TIMM50 timm50 (Catalog #AAA9212488) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 74-104. The TIMM50 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIMM50 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TIMM50 timm50 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIMM50, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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