Western Blot (WB)
(Western Blot: Sample: Rat Kidney lysate; Primary Ab: 1ug/ml Rabbit Anti-Human TP Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Human Thromboxane Receptor Polyclonal Antibody | anti-TP antibody
Thromboxane Receptor (TP) Polyclonal Antibody
Gene Names
TBXA2R; TXA2-R; BDPLT13
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Synonyms
Thromboxane Receptor; Polyclonal Antibody; Thromboxane Receptor (TP) Polyclonal Antibody; TBXA2R; TXA2-R; Thromboxane A2 Receptor; Prostanoid TP receptor; anti-TP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Form/Format
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Concentration
500ug/mL (varies by lot)
Applicable Applications for anti-TP antibody
WB; IHC; ICC; IP.
Application Notes
Western blotting: 0.5-2(Ug/mL;1:250-1000
Immunohistochemistry: 5-20(Ug/mL;1:25-100
Immunocytochemistry: 5-20(Ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 5-20(Ug/mL;1:25-100
Immunocytochemistry: 5-20(Ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Organism Species
Homo sapiens (Human)
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant Thromboxane Receptor (Pro3~Ser324) expressed in E.coli
Cross Reactivity
Human, Rat
Conjugated Antibody
The APC-Cy7 conjugated antibody version of this item is also available as catalog #MBS2068372
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Rat Kidney lysate; Primary Ab: 1ug/ml Rabbit Anti-Human TP Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Rat Kidney lysate; Primary Ab: 1ug/ml Rabbit Anti-Human TP Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Kidney Tissue))
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
thromboxane A2 receptor isoform alpha
NCBI Official Synonym Full Names
thromboxane A2 receptor
NCBI Official Symbol
TBXA2R
NCBI Official Synonym Symbols
TXA2-R; BDPLT13
NCBI Protein Information
thromboxane A2 receptor
UniProt Protein Name
Thromboxane A2 receptor
Protein Family
UniProt Gene Name
TBXA2R
UniProt Synonym Gene Names
TXA2-R
NCBI Description
This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Uniprot Description
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.
Research Articles on TP
Similar Products
Product Notes
The TP tbxa2r (Catalog #AAA2032166) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Thromboxane Receptor (TP) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thromboxane Receptor can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2(Ug/mL;1:250-1000Immunohistochemistry: 5-20(Ug/mL;1:25-100
Immunocytochemistry: 5-20(Ug/mL;1:25-100
Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the TP tbxa2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thromboxane Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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