Rabbit anti-Rat Thrombin Activatable Fibrinolysis Inhibitor (TAFI) Polyclonal Antibody | anti-TAFI antibody
FITC-Linked Polyclonal Antibody to Thrombin Activatable Fibrinolysis Inhibitor (TAFI)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes carboxypeptidase B, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functional enzyme, and secreted into plasma. [provided by RefSeq, Jan 2016]
Uniprot Description
CPB2: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.17.20; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14|14 D3
Cellular Component: extracellular space
Molecular Function: carboxypeptidase activity; metallocarboxypeptidase activity
Biological Process: fibrinolysis; negative regulation of fibrinolysis; proteolysis; response to heat
Research Articles on TAFI
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Product Notes
The TAFI cpb2 (Catalog #AAA2045068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FITC-Linked Polyclonal Antibody to Thrombin Activatable Fibrinolysis Inhibitor (TAFI) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Thrombin Activatable Fibrinolysis Inhibitor (TAFI) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the TAFI cpb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thrombin Activatable Fibrinolysis Inhibitor (TAFI), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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