Western Blot (WB)
(WB Suggested Anti-PRKRIR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Rabbit THAP12 Polyclonal Antibody | anti-THAP12 antibody
THAP12 Antibody - N-terminal region
Gene Names
THAP12; DAP4; THAP0; PRKRIR; P52rIPK
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Applications
Western Blot
Purity
Affinity Purified
Synonyms
THAP12; Polyclonal Antibody; THAP12 Antibody - N-terminal region; anti-THAP12 antibody
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: VENCRRADLEDKTPDQLNKHYRLCAKHFETSMICRTSPYRTVLRDNAIPT
Sequence Length
761
Applicable Applications for anti-THAP12 antibody
Western Blot (WB)
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRIR
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-PRKRIR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-PRKRIR Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Related Product Information for anti-THAP12 antibody
This is a rabbit polyclonal antibody against PRKRIR. It was validated on Western Blot using a cell lysate as a positive control.
Product Categories/Family for anti-THAP12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
88kDa
NCBI Official Full Name
52 kDa repressor of the inhibitor of the protein kinase
NCBI Official Synonym Full Names
THAP domain containing 12
NCBI Official Symbol
THAP12
NCBI Official Synonym Symbols
DAP4; THAP0; PRKRIR; P52rIPK
NCBI Protein Information
52 kDa repressor of the inhibitor of the protein kinase
UniProt Protein Name
52 kDa repressor of the inhibitor of the protein kinase
Protein Family
UniProt Gene Name
PRKRIR
UniProt Synonym Gene Names
DAP4; P52RIPK; THAP0; p52rIPK; p58IPK-interacting protein
UniProt Entry Name
P52K_HUMAN
Uniprot Description
PRKRIR: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR- inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, regulatory subunit; Cell cycle regulation
Chromosomal Location of Human Ortholog: 11q13.5
Cellular Component: nucleus
Molecular Function: protein dimerization activity; DNA binding; metal ion binding
Biological Process: negative regulation of cell proliferation; response to stress; signal transduction
Research Articles on THAP12
Similar Products
Product Notes
The THAP12 prkrir (Catalog #AAA3212871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The THAP12 Antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's THAP12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the THAP12 prkrir for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: VENCRRADLE DKTPDQLNKH YRLCAKHFET SMICRTSPYR TVLRDNAIPT. It is sometimes possible for the material contained within the vial of "THAP12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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