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Immunohistochemistry (IHC) (Anti-TGM7 / Transglutaminase 7 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human, Mouse TGM7 / Transglutaminase 7 Polyclonal Antibody | anti-TGM7 antibody

Rabbit Polyclonal to Human TGM7 / Transglutaminase 7

Gene Names
TGM7; TGMZ
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
TGM7 / Transglutaminase 7; Polyclonal Antibody; Rabbit Polyclonal to Human TGM7 / Transglutaminase 7; Anti-TGM7 / Transglutaminase 7 Antibody (Internal) IHC-plus; TGM7; TG(Z); TGase Z; TGase-7; Transglutaminase Z; TGMZ; TGZ; Transglutaminase-7; Transglutaminase 7; Human TGM7; anti-TGM7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Human TGM7 / Transglutaminase 7. TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist; this antibody will recognize both isoforms.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
710
Applicable Applications for anti-TGM7 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, ICC (2.5 ug/ml), IF (10 ug/ml), IHC-P (5 ug/ml), WB (1 ug/ml)
Target Species
Human
Immunogen Description
A 13 amino acid peptide near the center of human TGM7
Immunogen Type
Synthetic peptide
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-TGM7 / Transglutaminase 7 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-TGM7 / Transglutaminase 7 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 µg/mL.)

Immunofluorescence (IF) (Immunofluorescence of TGM7 in A549 cells with TGM7 antibody at 10 µg/mL.)

Immunocytochemistry (ICC)

(Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 µg/mL.)

Immunocytochemistry (ICC) (Immunocytochemistry of TGM7 in A549 cells with TGM7 antibody at 2.5 µg/mL.)

Western Blot (WB)

(Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 ug/ml.)

Western Blot (WB) (Western blot analysis of TGM7 in human lung tissue lysate with TGM7 antibody at 1 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
79,941 Da
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase Z
NCBI Official Synonym Full Names
transglutaminase 7
NCBI Official Symbol
TGM7
NCBI Official Synonym Symbols
TGMZ
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase Z; TGZ; TGase Z; TGase-7; transglutaminase Z; transglutaminase-7
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase Z
UniProt Gene Name
TGM7
UniProt Synonym Gene Names
TG(Z); TGZ; TGase Z; TGase-7
UniProt Entry Name
TGM7_HUMAN

NCBI Description

Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).[supplied by OMIM, Jul 2002]

Uniprot Description

TGM7: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent.

Protein type: Transferase; EC 2.3.2.13

Chromosomal Location of Human Ortholog: 15q15.2

Molecular Function: protein-glutamine gamma-glutamyltransferase activity; metal ion binding

Biological Process: peptide cross-linking

Research Articles on TGM7

Similar Products

Product Notes

The TGM7 tgm7 (Catalog #AAA248255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human TGM7 / Transglutaminase 7 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TGM7 / Transglutaminase 7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). ELISA, ICC (2.5 ug/ml), IF (10 ug/ml), IHC-P (5 ug/ml), WB (1 ug/ml). Researchers should empirically determine the suitability of the TGM7 tgm7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGM7 / Transglutaminase 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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