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Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, using TF2H1 antibody.)

Rabbit anti-Human, Mouse TF2H1 Polyclonal Antibody | anti-TF2H1 antibody

TF2H1 Antibody

Gene Names
GTF2H1; P62; BTF2; TFB1; TFIIH
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TF2H1; Polyclonal Antibody; TF2H1 Antibody; TFIIH basal transcription factor complex p62 subunit; Basic transcription factor 62 kDa subunit; BTF2-p62; General transcription factor IIH polypeptide 1; GTF2H1; anti-TF2H1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TF2H1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
548
Applicable Applications for anti-TF2H1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from N-terminal of human TF2H1.
Target Name
TF2H1
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells, using TF2H1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, using TF2H1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue using TF2H1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human brain tissue using TF2H1 antibody.)
Related Product Information for anti-TF2H1 antibody
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.Fischer L., Science 257:1392-1395(1992).Ota T., Nat. Genet. 36:40-45(2004).Liu J., Mol. Cell 5:331-341(2000).
Product Categories/Family for anti-TF2H1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,738 Da
NCBI Official Full Name
general transcription factor IIH subunit 1
NCBI Official Synonym Full Names
general transcription factor IIH, polypeptide 1, 62kDa
NCBI Official Symbol
GTF2H1
NCBI Official Synonym Symbols
P62; BTF2; TFB1; TFIIH
NCBI Protein Information
general transcription factor IIH subunit 1
UniProt Protein Name
General transcription factor IIH subunit 1
UniProt Gene Name
GTF2H1
UniProt Synonym Gene Names
BTF2; BTF2 p62
UniProt Entry Name
TF2H1_HUMAN

Uniprot Description

GTF2H1: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 11p15.1-p14

Cellular Component: nucleoplasm; holo TFIIH complex

Molecular Function: RNA polymerase subunit kinase activity; DNA-dependent ATPase activity; protein binding; protein kinase activity

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; termination of RNA polymerase I transcription; DNA repair; regulation of gene expression, epigenetic; protein amino acid phosphorylation; mRNA capping; negative regulation of gene expression, epigenetic; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; RNA elongation from RNA polymerase II promoter; nucleotide-excision repair, DNA damage removal; positive regulation of transcription from RNA polymerase II promoter; gene expression; regulation of cyclin-dependent protein kinase activity; transcription initiation from RNA polymerase I promoter

Research Articles on TF2H1

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Product Notes

The TF2H1 gtf2h1 (Catalog #AAA9406058) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TF2H1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TF2H1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the TF2H1 gtf2h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TF2H1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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