Immunohistochemistry (IHC)
((4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.)
Goat Tensin 1/TNS1 Polyclonal Antibody | anti-TNS1 antibody
Goat anti-Tensin 1/TNS1 Antibody
Gene Names
TNS1; TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; PPP1R155
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA, Immunohistochemistry
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Tensin 1/TNS1; Polyclonal Antibody; Goat anti-Tensin 1/TNS1 Antibody; Goat Anti-Tensin 1 (aa902-914) Antibody; TNS1; tensin 1; TNS; tensin; MGC88584; PRO0929; FLJ10923; DKFZP434G162; MSTP091; DKFZp586K0617; MST091; MST122; MST127; MSTP122; MSTP127; MXRA6; Matrix-remodelling-associated protein 6; matrix-remodelling associated 6; TNS1 antibody; tensin 1 antibody; TNS antibody; tensin antibody; MGC88584 antibody; PRO0929 antibody; FLJ10923 antibody; DKFZP434G162 antibody; MSTP091 antibody; DKFZp586K0617 antibody; MST091 antibody; MST122 antibody; MST127 antibody; MSTP122 antibody; MSTP127 antibody; MXRA6 antibody; Matrix-remodelling-associated protein 6 antibody; matrix-remodelling associated 6 antibody; Tensin 1; Tensin 1 / TNS1; anti-TNS1 antibody
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
VSKVMLNAGQKR
Sequence Length
1735
Applicable Applications for anti-TNS1 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 2000.
Immunohistochemistry: In paraffin embedded Human Kidney shows weak staining of the basement membranes of convoluted tubules. Recommended concentration, 4-6ug/ml.
Western Blot: Preliminary experiments in Human Heart, Kidney and Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Immunohistochemistry: In paraffin embedded Human Kidney shows weak staining of the basement membranes of convoluted tubules. Recommended concentration, 4-6ug/ml.
Western Blot: Preliminary experiments in Human Heart, Kidney and Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Immunogen
Peptide with sequence C-VSKVMLNAGQKR, from the C Terminus of the protein sequence according to NP_072174.3.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Immunohistochemistry (IHC)
((4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.)
Immunohistochemistry (IHC)
((4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,240 Da
NCBI Official Full Name
tensin-1 isoform 1
NCBI Official Synonym Full Names
tensin 1
NCBI Official Symbol
TNS1
NCBI Official Synonym Symbols
TNS; MXRA6; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; PPP1R155
NCBI Protein Information
tensin-1
UniProt Protein Name
Tensin-1
Protein Family
UniProt Gene Name
TNS1
UniProt Synonym Gene Names
TNS
UniProt Entry Name
TENS1_HUMAN
NCBI Description
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Uniprot Description
tensin 1: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.
Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q35-q36
Cellular Component: cell surface; cytoplasm; cytoskeleton; focal adhesion
Molecular Function: actin binding; protein binding
Biological Process: cell-substrate junction assembly
Research Articles on TNS1
Similar Products
Product Notes
The TNS1 tns1 (Catalog #AAA420337) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Tensin 1/TNS1 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's Tensin 1/TNS1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunohistochemistry (IHC). Peptide ELISA: Antibody detection limit dilution 1: 2000. Immunohistochemistry: In paraffin embedded Human Kidney shows weak staining of the basement membranes of convoluted tubules. Recommended concentration, 4-6ug/ml. Western Blot: Preliminary experiments in Human Heart, Kidney and Skeletal Muscle lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Researchers should empirically determine the suitability of the TNS1 tns1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: VSKVMLNAGQ KR. It is sometimes possible for the material contained within the vial of "Tensin 1/TNS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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